Jun 26, 2024 · SS-31 is a potent therapeutic peptide that treats mitochondrial disorders and reverses mitochondrial damage. SS-31 mitigates the risk of oxidative damage by reducing …

Jan 27, 2022 · SS-31 (a.k.a. Elampretide, Bendavia, MPT-141) is a synthetic tetrapeptide (i.e. 4 amino acids long) that was discovered by scientists Hazel H. Szeto and Peter W. Schiller in …

Our results reveal that SS-31 exerts beneficial effects on the leukocytes of T2D patients by reducing oxidative stress, leukocyte-endothelium interactions, NFκB and TNFα and by increasing SIRT1 levels. These actions support its use as a potential agent against CVD risk.

Nov 18, 2022 · One of the most promising therapeutic approaches for BTHS includes the mitochondria-targeted tetrapeptide SS-31, which interacts with CL. Here, we used TAFAZZIN knockdown (Taz KD) mice to...

SS-31对 缺血再灌注损伤 、 神经退行性疾病 、心力衰竭、肌肉老化等和自由基有关的疾病具有治疗效果。 SS-31 是一种针对线粒体的分子。 它与心磷脂相互作用以重新激活缺血线粒体。 同时SS-31也是一种细胞穿膜肽。 最近很多人咨询的一个肽，线粒体靶向抗氧化剂SS-31肽。 （使用氨基树脂，采用Fmoc固相多肽合成方法，从右往左依次合成，左边第二个氨基酸Dmt，使用保护氨基酸原料为Fmoc-Tyr (2,6-Me2,4-tBu)-OH，CAS号：1043043-79…

Oct 30, 2024 · There are many variations of this protocol. A typical one seems to be ss31 at 4mg for some period of time - 21 days, 28 days, 1 month, 2 months - some do it daily, some 5 days …

Jan 8, 2021 · SS-31对缺血再灌注损伤、神经退行性疾病、心力衰竭、肌肉老化等和自由基有关的疾病具有治疗效果。 SS-31 是一种针对线粒体的分子。 它与心磷脂相互作用以重新激活缺血线粒体。 同时SS-31也是一种细胞穿膜肽。 参考文献： https://onlinelibrary.wiley.com/doi/10.1111/cbdd.12003. 这个肽在各大检索平台上，一抓一大把，小编就不列出文献链接了。 SS-31肽是一种心磷脂过氧化物酶抑制剂和线粒体靶向肽。 它 …

Oct 16, 2024 · I am 58 years old and started SS-31 to address terrible Tirz fatigue. I did have to titrate up the SS-31 slowly, over a few days, going too fast caused a little brain fog. Amazing results and might even consider extending my SS31 dosing beyond the typical four-week protocol.

通过减少神经元的死亡并改善神经功能，SS31能够有效减缓疾病进程，提升患者的生活质量。 尤其在帕金森病的模型中，SS31通过减少线粒体氧化损伤，显著改善了运动功能的恢复，给未来的临床治疗带来了新的希望。 其次，心脏保护是SS31应用的另一个关键领域。

SS-31 is rapidly taken up by skeletal muscle, with maximal levels observed 30 min after subcutaneous (sc) administration. Maximal ATP production and P/ O coupling returned to levels seen in 5-month-old mice within 1 h after SS-31 treatment. SS-31 also restored maximal ATP production in aged mice but had no observable effect in young mice.