BRD2 - Wikipedia
Bromodomain-containing protein 2 is a protein that in humans is encoded by the BRD2 gene. BRD2 is part of the Bromodomain and Extra-Terminal motif (BET) protein family that also …
BRD2 Gene - GeneCards | BRD2 Protein | BRD2 Antibody
2024年12月24日 · BRD2 (Bromodomain Containing 2) is a Protein Coding gene. Diseases associated with BRD2 include Nut Midline Carcinoma and Adolescence-Adult Electroclinical …
Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional ...
In this study, we report that the BET family members Brd2 and Brd4 exert distinct genomic functions at genes whose transcription they co-regulate during mouse T helper 17 (Th17) cell …
BRD2 bromodomain containing 2 [ Homo sapiens (human) ]
2024年12月10日 · Title: BRD2 induces drug resistance through activation of the RasGRP1/Ras/ERK signaling pathway in adult T-cell lymphoblastic lymphoma. Bromodomain …
BRD2 compartmentalizes the accessible genome - Nature
2022年4月11日 · With chemical–genetic perturbations, super-resolution imaging and Micro-C genomic interaction mapping, we show that the BET family scaffold protein BRD2 has the …
生命学院季雄课题组揭示BRD2介导RNA聚合酶II转录的功能机理
2022年6月25日 · brd2/3/4/t是哺乳动物细胞中bet蛋白家族成员，它们均包含两个保守的溴结构域和一个et结构域，是多种疾病抑制剂的关键靶点。 BRD4通过招募转录延伸因子pTEF-b调控PolII …
BRD2 bromodomain containing 2 [ (human)] - National Center for ...
Results provide evidence that BRD2 is a positive regulator of epithelial-to-mesenchymal transition in breast cancer cells. the bromodomain protein BRD2 is recruited to DNA double-strand breaks.
The C-terminal domain of Brd2 is important for chromatin …
Brd2 is specifically localized at promoters of target genes, and our data show that Brd2 interaction with chromatin cannot be explained solely by histone acetylation. Using coimmunoprecipitation …
Bromodomain and Extraterminal Domain Protein 2 in Multiple …
2024年6月1日 · In this review, we provide an overview of the structural and physiologic characteristics of bromodomain (BD) and extraterminal domain (BET) protein 2 (BRD2). …
BRD2 interconnects with BRD3 to facilitate Pol II transcription ...
Here, we used acute protein degradation and quantitative genomic and proteomic approaches to investigate the primary functions of BRD2 in transcription. We report that BRD2 is required for …