BT-20 (亦稱 ATCC HTB-19) 是較常應用於乳癌 臨床前研究 的 人類 三陰性乳癌 細胞系 [1]，最初在1958年從一位74歲的 女性 乳癌 患者 中分離出來 [2]。 目前已知BT-20細胞的 6號染色體 、 11號染色體 和20號 染色體 具有擴增區域 (amplified regions) ，並且大多數細胞為 超二倍體。 BT-20 細胞 對WNT3和WNT78呈 陽性 反應，並且對 雌激素受體 呈 陰性，但是會表達5 外顯子 缺失的 雌激素 信使核糖核酸 [3]。 有 研究 [谁？ ] 指出 腫瘤壞死因子-α 能夠抑制BT-20細胞的增殖。

DTG inhibited the expression of HERV-K in multiple human cancer cell lines and the mouse mammary tumor virus (MMTV) in the murine 4T1 mammary cancer cell line. We chose the fast-growing BT-20 cell line as a model to study the in vitro antiproliferative mechanisms of DTG.

BT-20 cells were isolated in 1958 from a breast tumor of a 74-year-old, White, female breast cancer patient. Use these cells in your breast cancer and immuno-oncology research.

2024年3月11日 · We evaluated the liver and lung metastasis of human TNBC cell lines MDA-MB-231, MDA-MB-468, BT549, Hs578T, BT20, and SUM159 in immunocompromised mice. We characterized each cell line's cell morphology, proliferation, and motility in 2D and 3D to determine the variation in these parameters between cell lines.

Our results showed that the primary tumors in MTAP-knockdown group (BT20-shMTAP) grew faster than the control group (Figure 3B). The tumor volume caused by BT20-shMTAP cells (19.38±0.41 mm 3) was significantly larger than tumors (10.03±1.15 mm 3) induced by control cells (P<0.0001, Figure 3C).

Cultivation of human breast carcinomas. Transplantation of a human mammary carcinoma cell line (BT 20) into nude mice. Absence of HeLa cell contamination in 169 cell lines derived from human tumors. Human breast tumor cells in culture; new concepts in mammary carcinogenesis.

2015年5月15日 · In this study, the breast carcinoma cell-line (BT20) cells with an ultra-low abundance range were captured by streptavidin (STR)-functionalized silicon nanowire (SiNW) platforms for evaluation of capture efficiency. A capture efficiency of …

2015年5月15日 · In this study, the breast carcinoma cell-line (BT20) cells with an ultra-low abundance range were captured by streptavidin (STR)-functionalized silicon nanowire (SiNW) platforms for evaluation of capture efficiency. A capture efficiency of …

BT-20 is a breast cancer cell line derived from a 74-year-old human female in 1958 by E.Y. Lasfargues and L. Ozzello. [1] The cells technically came from a triple-negative breast cancer, which was caused by an invasive ductal carcinoma in the mammary gland.

2024年3月19日 · Our study investigates the antimetastatic potential of the curcumin analog NC2603 in breast cancer cells, utilizing BT-20 cells known for their migratory properties. Cell viability assessments were performed using the MTT reduction method, while migration inhibition was evaluated through scratch and Transwell migration assays.