促凋亡基因代表成员 Bax，能够编码 α、β、γ、δ、ε、σ 共 6 种 Bax 蛋白亚型。Bax 基因编码的具有生物学活性的 Baxα （21 kD），是 Bax 基因在细胞中发挥促凋亡作用的主要表达形式。

Polyclonal Antibody for studying Bax. Validated for IP, WB, WB. Available in 2 sizes. Highly specific and rigorously validated in-house, Bax Antibody (CST #2772) is ready to ship.

60267-1-Ig targets BAX in WB, IHC, IP, CoIP, ELISA, ICC applications and shows reactivity with human, mouse, rat samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Bax是一种促凋亡蛋白，上调Bax蛋白水平可以促进细胞凋亡。 在通过线粒体应激诱导的细胞凋亡中Bax起关键作用。 Bax可以形成寡聚体，然后从细胞浆中转移到线粒体膜上；通过和线粒体膜上的一些pore proteins相互作用，增强线粒体的通透性 (permeability)；最后导致细胞色素c释放 (cytochrome c release)、caspase-9激活以及后续的其它caspase激活和最终的细胞凋亡。 Bax可以和Bcl-2形成多聚体，来调节线粒体膜的通透性，最终调节细胞的凋亡或存活。 配套提供 …

Bax抗体（B-9）是一种小鼠单克隆IgG2b kappa轻链抗体，可通过蛋白质印迹、免疫沉淀、免疫荧光、免疫组织化学和流式细胞术等方法检测小鼠、大鼠和人源Bax蛋白。

Detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa). Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein.

Polyclonal Antibody for studying Bax. Validated for IP, WB. Highly specific and rigorously validated in-house, Bax Antibody (CST #2774) is ready to ship.

Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane.

Invitrogen Anti-Bax Monoclonal (6A7), eBioscience™, Catalog # 14-6997-82. Tested in Western Blot (WB) applications. This antibody reacts with Human, Mouse, Non-human primate, Rat samples. Supplied as 100 µg purified antibody (0.5 mg/mL).