2024年9月25日 · Blood–brain barrier disruption (BBBD) is an important pathophysiological change that occurs during the acute phase of ischemic stroke. Reperfusion that restores blood–brain barrier permeability (BBBP) also produces reperfusion injury, which worsens neurological function [4].

Osmotic blood-brain barrier disruption (BBBD) therapy was first introduced in the early 1980s as a method to increase the penetration of chemotherapeutics into the central nervous system (CNS). 1, 2 The procedure involves intra-arterial injection of a warmed, hypertonic mannitol solution to disrupt the tight junctions of vascular endothelial cel...

Blood–brain barrier disruption is the surgical process whereby drugs are used to create openings between cells in the blood–brain barrier. [1] The blood–brain barrier (BBB) is protected by a network of blood vessels and tissue that shields it from harmful substances. This protection also stops anti-cancer drugs from getting to the brain.

2019年4月11日 · We propose BBBD mapping as a valuable tool for detection of subtle brain ischemia and a promising predictive biomarker required for risk stratification and stroke prevention.

Blood–brain barrier disruption treatment is a promising option for primary central nervous system lymphoma with an acceptable toxicity profile. Keywords: BBBD, PCNSL, ASCT. 1. Introduction.

Blood-brain-barrier disruption (BBBD) aims to compromise transiently the BBB using chemical or mechanical means to allow the passage of circulating therapeutic molecules and biomarkers into, and less frequently, out of the parenchyma (Table 1).

2024年10月8日 · 英语缩略词“BBBD”经常作为“Blood Brain Barrier Disruption”的缩写来使用，中文表示：“血脑屏障破坏”。 本文将详细介绍英语缩写词BBBD所代表英文单词，其对应的中文拼音、详细解释以及在英语中的流行度。 此外，还有关于缩略词BBBD的分类、应用领域及相关应用示例等。 以上为Blood Brain Barrier Disruption英文缩略词 BBBD 的中文解释，以及该英文缩写在英语的流行度、分类和应用领域方面的信息。

Blood-brain barrier disruption (BBBD) is currently used clinically to increase the delivery of chemotherapeutic agents and in some cases monoclonal antibodies (mAb) for the treatment of brain tumors.

2019年2月26日 · Focused ultrasound combined with microbubble for blood-brain barrier disruption (FUS-BBBD) is a promising technique for noninvasive and localized brain drug delivery. This study demonstrates that...

We have witnessed the rise of transcranial focused ultrasound (tFUS) technology that temporarily and reversibly disrupts the blood-brain-barrier (BBB) in the brain with exceptional control over …