The benzodiazepine conversion calculator adjusts doses between converting oral benzodiazepines.

In the UK clobazam (Frisium) and clonazepam (Rivotril) are licensed for use as anti-epileptics only. These drugs are chemically different from benzodiazepines but have the same effects on the body and act by the same mechanisms.

Dosing (Adults): Seizure disorders: Initial daily dose not to exceed 1.5 mg given in 3 divided doses; may increase by 0.5-1 mg every third day until seizures are controlled or adverse effects seen (maximum: 20 mg/day). Usual maintenance dose: 0.05-0.2 …

Benzodiazepines have a narrow therapeutic window - dose adjustments should be made by an experienced clinician. This calculator is not a substitute for clinical experience and must be used in conjunction with reasonable clinical judgment. …

本品为bdz类抗焦虑药，随用药量增大而具有抗焦虑、镇静、催眠、抗惊厥、抗癫痫及中枢性肌肉松弛作用： ① 抗焦虑作用选择性很强，是氯氮䓬的5倍，这可能与其选择性地作用于大脑边缘系统，与中枢BDZ受体结合而促进 γ-氨基丁酸 （GABA）的释放或促进突触 ...

Benzodiazepines (BZD, BDZ, BZs), colloquially known as "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. They are prescribed to treat conditions such as anxiety disorders, insomnia, and seizures.

本品为新的BDZ类药物，具有同地西泮相似的药理作用，有抗焦虑、抗抑郁、镇静、催眠、抗惊厥及肌肉松弛等作用。 其抗焦虑作用比地西泮强10倍,作用机制可能与脑内β-肾上腺素受体有关。 本品口服吸收迅速而完全，1〜2小时即可达血药峰浓度，血浆半衰期为12〜18小时，2〜3天血药浓度达稳态。 血浆蛋白结合率约为80%。 吸收后分布于全身，并可透过胎盘屏障，乳汁中亦有药物。 经肝脏CYP3A酶系代谢为活性物质α-羟三唑安定,但浓度太低无临床意义。 最后自肾脏排出体 …

Using the modern ClinCalc ranged data, Xanax is 5-20 times stronger than Valium, and clonazepam is 1.25-80 times more powerful than temazepam.

2015年5月31日 · BZD作用於中樞神經系統 GABA-A受體上的 benzodiazepine receptor，增加神經元細胞膜氯離子的通透性，造成超極化的不反應狀態，達到神經抑制的作用。 表格中把院內有的口服 BZD品項從較短效的 Brotizolam (短效多記一個院內只有針劑的 Midazolam)，到中效的 Lorazepam, Alprazolam至長效的 Fludiazepam, Diazepam由上到下排列，適應症大同小異，幾乎都是焦慮或失眠，除了 Clonazepam為癲癇治療用。 起始作用時間約半小時。

Select the benzodiazepine you're converting from and its dose and the drug you're converting, and hit submit. Last updated June 21 2023 05:13:58. Disclaimer: This website does not …