Charles Herbert Best (February 27, 1899 – March 31, 1978), was an American-Canadian medical scientist and one of the co-discoverers of insulin with Frederick Banting. He served as the chair of the Banting and Best Department of Medical Research at the University of Toronto and was further involved in research concerning choline and heparin.

2025年2月23日 · Charles H. Best (born February 27, 1899, West Pembroke, Maine, U.S.—died March 31, 1978, Toronto, Ontario, Canada) was a physiologist who, with Sir Frederick Banting, was one of the first to obtain (1921) a pancreatic extract of insulin in a form that controlled diabetes in dogs. The successful use of insulin in treating human patients followed.

2015年1月1日 · Charles Herbert Best was an American-Canadian biochemist and physiologist, most well known for his work in discovering insulin with Frederick Grant Banting at the University of Toronto, Canada.

F G Banting, C H Best, J B Collip, W R Campbell, A A Fletcher. PMID: 20314060 PMCID: PMC1524425 No abstract available ...

2002年6月28日 · Macleod also assigned Charles Best, a young student, to work as Banting's assistant for the summer. During the summer of 1921, Banting and Best made remarkable progress, and by fall they had isolated material from pancreas extracts that dramatically prolonged the lives of dogs made diabetic by removal of the pancreas.

Since the year 1889, when von Mering and Minkowski produced severe and fatal diabetes by total removal of the pancreas in dogs, many investigators have endeavoured to obtain some beneficial effect in diabetes mellitus, either by feeding pancreas, or by administration of pancreatic extracts. This content is only available via PDF.

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