Optical coherence tomography (OCT): Can be used to localize the vitelliform lesion to the subetinal space, demonstrate thickening of the cone outer segments, and can be used to evaluate for fluid associated with CNV.

2005年2月1日 · Best's vitelliform macular dystrophy is characterized by abnormal retinal deposition of lipofuscin, the exact location of which remains to be definitely elucidated, notwithstanding several clinical and optical coherence tomography (OCT) reports. 1, 2, 3, 4 In this report we present new OCT findings of “pseudohypopyon” and “scrambled-egg ...

2010年12月2日 · Best’s disease is a rare, incurable, autosomal dominant, slowly developing vitelliform (yolk-like) macular dystrophy associated with central visual disturbance and loss. The disease is limited to macular anomalies, excluding systemic associations.

Best disease is an inherited disease that affects the retinas of your eyes. It causes the macula, which is the central part of the retina, to degrade. This means that you can have problems with your central vision, or seeing things that are right in front of you. Best disease may not affect peripheral (side) vision.

Best's vitelliform macular dystrophy is characterized by abnormal retinal deposition of lipofuscin, the exact location of which remains to be definitely elucidated, notwithstanding several clinical and optical coherence tomography (OCT) reports. 1–4 In this report we present new OCT findings of “pseudohypopyon” and “scrambled-egg ...

2022年1月1日 · OCT Features: OCT can distinguish differences between the various stages of Best disease. In the vitelliform stage, the subretinal material exhibits a mixture of both hyper-reflective and hyporeflective material.

From top to bottom are subclinical (a, stage I), vitelliform (b, stage II), pseudohypopyon (c, stage III), vitelliruptive (d, stage IV), and macular atrophy (e, stage V) stages. Beginning in stage...

These new OCT findings could explain the retention of good visual acuity in the "pseudohypopyon stage" and the loss of visual acuity in the "scrambled egg" stage of Best's disease.

Bests disease, is a hereditary retinal dystrophy involving the retinal pigment epithelium (RPE), and leads to a characteristic bilateral yellow “egg-yolk” appearance of the macula. This disease tends to present itself in childhood or early adulthood and usually portends a good visual prognosis.

2023年3月27日 · Optical Coherence Tomography (OCT) and adaptive optics imaging revealed that vitelliform lesions are characterized by progressive changes in the cone mosaic corresponding to a thinning of the outer nuclear layer and then disruption of the ellipsoid zone, which are associated with a decreased sensitivity and visual acuity.