2006年10月1日 · Extended-spectrum β-lactamases (ESBLs) are well known for their role in bacterial resistance to β-lactam antibiotics. They occupy a wide variety of geographical niches and occur almost freely in some nosocomial environments.

Inspired by the experimental realization of monolayer β-phase GeSe which has a moderate bandgap and excellent transport properties, based on the first-principles calculations, we identify a new class of compelling two-dimensional (2D) materials, β-MX (GeS, GeSe, SnS and SnSe), which not only exhibit good feasibility for experimental ...

2022年9月1日 · The results show that the electrical conductivity of β -GeS monolayer can be enhanced after adsorbing the alkali metal atoms owing to the semiconductor-to-metal transition. The low diffusion barriers of alkali metal atoms on the β -GeS surface indicate a rapid charge/discharge rate without metal clustering.

2017年1月26日 · Here we report the electronic and structural properties of β-GeSe, a previously unreported polymorph of GeSe, with a unique crystal structure that displays strong two-dimensional structural features. β-GeSe is made at high pressure and temperature and is stable under ambient conditions.

2018年10月1日 · GES-16 varies from GES-5 by a single amino acid substitution (Gln38Glu). To gain insights about the role of this mutation in conferring distinct β-lactams hydrolysis profile, we compared the kinetic constants for GES-5 and -16 against several β-lactam antibiotics.

2023年4月1日 · GES β-lactamases confer β-lactam resistance, but not all variants have carbapenemase activity. The GES family includes 57 variants (Naas et al., 2017) that differ from each other by one to four Single Nucleotide Polymorphisms (SNPs).

The low diffusion barriers of alkali metal atoms on the β-GeS surface indicate a rapid charge/discharge rate without metal clustering. Moreover, the low average open-circuit voltage (0.211 V) and a high theoretical capacity (1024 mAh⋅g−1) for Na suggest that the β-GeS monolayer is a promising anode material for Na-ion batteries with high ...

We compared the activities of GES-1, GES-11, GES-12, GES-14, and GES-5 against compounds representing the four major families of β-lactam antibiotics, namely, penicillins, cephalosporins, carbapenems, and monobactams.

2024年3月13日 · Explore in 3D: Structure | Sequence Annotations | Electron Density | Validation Report | Ligand Interaction (EPE) Biological assembly 1 assigned by authors.

In the present study, we investigated the prevalence of GES-type β-lactamases in ESBL-producing Enterobacteriaceae clinical isolates; two new alleles (GES-19 and GES-20) were identified in a plasmid-encoded class 1 integron (In724).