Fibroblast growth factors (FGFs) are a family of heparin-binding growth factors that includes at least 22 structurally related members, of which acidic fibroblast growth factor (aFGF) and basic fibroblast growth factor (bFGF) are the best-known members.

bFGF是重要的促有丝分裂的因子，也是形态发生和分化的诱导因子，主要拥有四大生物学作用：（1）促进血管生成；（2）促进创伤愈合与修复；（3）促进组织再生；（4）参与神经再生等。 作为细胞分裂原，bFGF体外作用十分强烈。 在细胞大规模培养领域，碱性成纤维细胞生长因子是胚胎干细胞培养基中的一个重要成分，其作用为使细胞在无血清培养基中保持未分化的状态。 但天然的bFGF在组织中含量极微，从组织中提取则成本高、产量低，因此目前均采用 基因工程 技 …

成纤维细胞生长因子（fibroblast growth factor,FGF）有几种异构体，在 动脉硬化 灶中起作用的主要是 bFGF （basic fibroblast growth factor），bFGF可以由 内皮细胞 、 平滑肌细胞 、 巨噬细胞 分泌。 它的作用是促进内皮细胞的游走和平滑肌细胞的增殖，不能使平滑肌细胞游走。 能够促进新血管形成，修复损害的内皮细胞。 FGF被认为是病灶形成促进因子，但从修复角度看它也有有利的一面。 定义 1： 由 垂体 和 下丘脑 分泌的多肽。 有酸性 (pI 5.6)和碱性 (pI 9.6)两种。 能促 …

2023年6月12日 · We demonstrate that a crystal of guanidinium tetrafluoroborate (C (NH 2) 3 BF 4) can be phase-matched throughout its entire optical transparency range and is able to generate harmonic light as...

Basic Fibroblast Growth Factor (bFGF) is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of physiologic angiogenesis....

Several growth factors, such as vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF, FGF2), and transforming growth factor beta (TGF-β), are involved in the main processes that fuel tumor growth, i.e., cell proliferation, angiogenesis, and metastasis, by activating important signaling pathways, including PLC-γ/PI3/Ca ...

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