Basic fibroblast growth factor (bFGF) is a prototypic member of the fibroblast growth factor family.

2023年6月20日 · Here, we evaluated the various functions of pluripotent stem cells (PSCs) by utilizing an engineered thermostable bFGF (TS-bFGF) that is thermally stable and maintains activity longer under mammalian culture conditions.

2023年5月5日 · 本发明属于成纤维细胞生长因子的技术领域，公开了一种bfgf热稳定性改造的方法，包括以下步骤：s1.目的基因合成；选取bfgf蛋白，将四个肝素结合位点从k突变为n，得到bfgfk突变体；s2.引物设计和合成；以bfgfk突变体的基因序列为模板，设计引物；在引物的两端 ...

Our study demonstrated that bFGF is a compelling regenerative therapy with competitive clinical efficacy and safety for deep second-degree burns and reduced treatment time, which is expected to reduce medical costs, particularly for deep second-degree burn patients.

Basic Fibroblast Growth Factor (bFGF) is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of physiologic angiogenesis....

1991年2月19日 · The three-dimensional structure of the 146-residue form of human basic fibroblast growth factor (bFGF), expressed as a recombinant protein in yeast, has been determined by x-ray crystallography to a resolution of 1.8 A. bFGF is composed entirely of beta-sheet structure, comprising a three-fold repeat of a four-stranded antiparallel beta-meander.

本发明属于成纤维细胞生长因子的技术领域，公开了一种bfgf热稳定性改造的方法，包括以下步骤：s1.目的基因合成；选取bfgf蛋白，将四个肝素结合位点从k突变为n，得到bfgfk突变体；s2.引物设计和合成；以bfgfk突变体的基因序列为模板，设计引物；在引物的两端 ...

Basic fibroblast growth factor (bFGF or FGF2), initially identified as a mitogen with prominent angiogenic properties, is now recognized as a multifunctional growth factor (3). It is clear that bFGF produces its biological effects in target cells by signaling through cell-surface FGF receptors. bFGF binds to all four FGF receptors.

一种bfgf热稳定性改造的方法,普纳思细胞(厦门)生物科技有限公司,202210915759.7,发明公布,本发明属于成纤维细胞生长因子的技术领域，公开了一种bfgf热稳定性改造的方法，包括以下步骤：s1.目的基因合成；选取bfgf蛋白，将四个肝素结合位点从k突变为n，得到bfgfk ...

Basic fibroblast growth factor (bFGF), a heparin-binding mitogen for mesoderm-derived cells, also acts as a mitogen, differentiation inducing and maintenance factor for many neuroectodermal cells including glial cells, neurons, paraneurons, and their tumor counterparts. The molecule is …