The 13th International Bion Conference | Upcoming International …
Join the 13th International Bion Conference in New York City, exploring Bion’s clinical thinking and the unthinkable. Discover innovative discussions connecting psychoanalysis, art, and …
2022 ASN肾脏周披露最新数据，BION-1301治疗显著降低IgA肾病 …
2022年11月16日 · BION-1301是结合并阻断增殖诱导配体（APRIL）的新型人源化单克隆抗体（mAb）， 具备潜在IgA肾病疾病修饰机制 （disease-modifying MOA）。 APRIL结合于B细胞 …
Bion-1301, a First-in-Class APRIL Neutralizing Antibody for the ...
2017年12月8日 · BION-1301 is a first-in-class humanized antibody targeting APRIL (TNFSF13). We demonstrated that BION-1301 inhibits proliferation and survival of tumor cells and …
A Study of BION-1301 in Adults With IgA Nephropathy
The primary objective of the study is to evaluate the effect of BION-1301 versus placebo on proteinuria in adults with IgA nephropathy. Participants will have assessments of safety and …
WCN24-1837 BEYOND: A PHASE 3, RANDOMIZED, DOUBLE-BLIND ...
Zigakibart (BION-1301) is a novel, humanized monoclonal antibody that blocks APRIL (a proliferation-inducing ligand), a cytokine that is elevated in patients with IgAN. APRIL …
Bion-1301: A Novel Fully Blocking APRIL Antibody for
2016年12月2日 · In vivo, BION-1301 was shown to suppress human APRIL induced T cell-independent B cell responses to NP-Ficoll. Biophysical and functional experiments indicated …
中国最强肾科Biotech，预判了诺华的预判 - 健康界
2023年7月7日 · bion-1301是一种抗april单克隆抗体，有望成为改变igan治疗现状的耀眼明星。 最新中期分析结果显示出BION-1301对IgAN患者的巨大疾病改善潜力，在合并分析的队列1和2 …
Bion-1301: A Novel Fully Blocking APRIL Antibody for the …
2016年12月2日 · In vivo, BION-1301 was shown to suppress human APRIL induced T cell-independent B cell responses to NP-Ficoll. Biophysical and functional experiments indicated …
WCN23-1175 UPDATED INTERIM RESULTS OF A PHASE 1/2 STUDY OF BION …
BION-1301 offers disease-modifying potential by directly targeting the initiating pathogenesis of IgAN by depleting pathogenic Gd-IgA1 and reducing proteinuria in patients with IgAN who …
Safety and tolerability of BION-1301 in adults with relapsed or ...
2019年5月26日 · Background: BION-1301 (BION) is first in class humanized monoclonal antibody directed against a proliferation-inducing ligand (APRIL) for treatment of relapsed/refractory …
- 某些结果已被删除