2022年1月3日 · Bone marrow mesenchymal stromal cells (BMSCs), identified as pericytes comprising the hematopoietic niche, are a group of heterogeneous cells composed of multipotent stem cells, including osteochondral and adipocyte progenitors. Nevertheless, the identification and classification are still controver …

2022年8月29日 · 骨髓间充质干细胞（ bone marrow derived mesenchymal stem cells，BMSC)是人们在哺乳动物的骨髓基质中发现的一种具有分化形成骨、软骨、脂肪、神经及成肌细胞的多种分化潜能的细胞亚群。

2024年4月9日 · Here, we successfully prepared human bone marrow mesenchymal stem cells derived CMVs (BMSC-CMVs) and human umbilical vein endothelial cells derived CMVs (EC-CMVs), which contain biologically ...

6 天之前 · Currently, bone defects remain a major challenge in clinical treatment. Recruiting target cells at the defect site and inducing them to differentiate into bone tissue are effective treatment methods. In previous studies, we used the CD271 antibody to construct bone marrow mesenchymal stem cell (BMSC) recruitment microspheres for the treatment of bone defects. However, the osteoconductivity of ...

2024年1月1日 · Bone marrow mesenchymal stem cells (BM-MSCs) are self-renewing cells with multidirectional differentiation potential. As the origin of osteogenic cell lineage, BM-MSCs are key cells involved in maintaining bone homeostasis and bone health. Research has illustrated the importance of mechanical stimuli in regulating the function of BM-MSCs.

Bone marrow-derived mesenchymal stem/stromal cells (BMSC) may facilitate bone repair through secretion of factors that stimulate endogenous repair processes or through direct contribution to new bone through differentiation into osteoblast-like ...

2019年1月1日 · Bone marrow mesenchymal stem cells (BMSCs) are signaled to differentiate to osteoblasts by transcription factors such Runx2 and Osx1 or to adipocytes by Pparγ and c/EBPα. BMSC-derived osteoblasts can further differentiate into mature osteocytes or may become lipid-storing cell types.

2021年5月17日 · Bone marrow mesenchymal stem cells (BMSCs) refer to a heterogeneous population of cells with the capacity for self-renewal. BMSCs have multi-directional differentiation potential and can differentiate into chondrocytes, osteoblasts, and adipocytes under specific microenvironment or mechanical regulation.

6 天之前 · Nonunion of fractures is a major unsolved problem in clinical treatment and prognosis of orthopedics. Bone marrow mesenchymal stem cell (BMSC) exosomes have been proven to be involved in mediating tissue and bone regeneration in a variety of diseases. However, the role of BMSC exosomes in fracture nonunion is unclear. BMSC exosomes were injected into a rat model of nonunion fracture, and the ...

2019年11月14日 · Bone marrow (BM) is a heterogeneous organ that contains, in addition to hematopoietic stem cells, BM stromal (also known as skeletal or mesenchymal) stem cells (BMSCs) and their...