
BNST GABAergic neurons modulate wakefulness over sleep and …
2024年3月19日 · It revealed that BNST GABAergic neurons displayed arousal-state-dependent alterations in population Ca 2+ signals, with high activity in both wakefulness and REM sleep. In addition, the Ca 2+...
A new GABAergic somatostatin projection from the BNST onto …
2020年6月18日 · We also discovered a novel GABAergic pathway from the anterior dorsal bed nuclei of stria terminalis (adBNST) to sNAc PV neurons. Optogenetic activation of these afferent terminals in sNAc produced...
终纹床核(bnst,又称bst)围绕前连合后肢 内段,头侧是伏隔核,尾侧是下丘脑外侧区,背侧是 隔复合体(隔核群的总称),和中央内侧杏仁核胚胎
Nat Commun | 揭示积极应对压力时,是如何刺激背后的这根神经 …
2021年8月9日 · 为了进一步研究运动行为和insular→BNST的联系,研究人员们在运动皮层注射顺向示踪病毒(被标记的神经元表达tdTomato),在BNST区注射逆向示踪病毒(被标记的神经元标记eGFP),3~6周后在insular观察到了tdTomato和GFP双阳性的细胞,验证了运动皮层→insular→BNST的 ...
Aversive contexts reduce activity in the ventral subiculum-BNST …
2022年8月8日 · The ventral subiculum (vSUB), the main output of the ventral hippocampus, encodes environmental cues and is critical for context processing. The bed nucleus of the stria terminalis (BNST) contributes to anxiety-like behaviors as well as context fear conditioning.
The altered sensitivity of acute stress induced anxiety-related ...
2022年11月1日 · The BNST, part of the extended amygdala, is a small structure in the medial basal forebrain. It plays a crucial role in anxiety (Davis et al., 2010). We confirmed that the PVT exerted extensive neuronal projections to the BNST, especially the dorsal part.
Disinhibition of PVN-projecting GABAergic neurons in AV region in BNST …
2020年7月1日 · In order to locate the PVN-projecting GABAergic neurons in BNST, we utilized the adenovirus tracer for neuronal connectivity, i.e. intra-PVN injection of Cre-dependent AAV-based retrograde with GABAergic neuron promoter (AAV-Vgat-cre, retro) in parallel to intra-BNST infusion of AAV-DIO-mCherry (Fig. 3 A).
Nature:一起学习最新激活下丘脑-垂体-肾上腺轴的神经机制|神经 …
2023年8月2日 · bnst被认为是hpa轴活性的关键调节剂,尤其是前腹侧bnst已被证明对hpa轴起抑制性制动作用。 那么,PVHCrh神经元的GABA能输入的来源是否是BNST? 研究人员发现,末端抑制BNSTvGAT→PVH神经元会强烈刺激血浆皮质酮水平[Fig.4i]。
The Lateral Hypothalamic and BNST GABAergic Projections to the …
2019年7月16日 · Here, we discover that suppressing the activity of GABAergic cells in the anterior ventrolateral periaqueductal gray (vlPAG), whether directly or through long-projection GABAergic inputs from either the bed nucleus of the stria terminalis (BNST) or the lateral hypothalamus (LH), is sufficient to promptly induce feeding behavior in well-fed mice.
【文献解读】Nature Communications丨BNST相关微通路参与炎症 …
2023年4月27日 · 本研究以野生型和PKC-δ-Cre的C57BL/6小鼠为研究对象,使用光遗传学和化学遗传学等多种实验技术, 发现椭圆部BNST(ovBNST)内的PKC-δ+神经元参与动物炎症引起的厌食症状,并对正常动物的摄食行为发挥双向调控作用。 ovBNST内的PKC-δ+神经元接受ARC、LPB和CEA等多个摄食相关脑区的传入调控,并对腹外侧BNST(vlBNST)内对摄食活动有重要作用的LH投射神经元的活动发挥抑制性调节作用。 结果显示,BNST内的PKC-δ+神经元群及相 …