2017年12月13日 · Β-cell replication in cultured islets was determined by BrdU incorporation (Cell proliferation kit, GE Health Care, Amersham, UK), and β-cell apoptosis by TUNEL assay (In …

2009年3月16日 · Reduced islet β-cell BrdU uptake in diabetic mice treated to restore normoglycemia. Diabetic Rip-CD80+GP+ mice were randomly assigned for treatment groups …

2019年3月4日 · In dispersed islet cells, but not in intact islets or in vivo, pro-proliferative conditions promoted both BrdU and γH2AX labeling, which could indicate DNA damage, DNA …

2019年3月4日 · In dispersed islet cells, but not in intact islets or in vivo, pro-proliferative conditions promoted both BrdU and γH2AX labeling, which could indicate DNA damage, DNA …

2014年5月5日 · As shown in the figures, the MSC-CM islets exhibited significantly increased BrdU incorporation compared to the untreated islets; pretreatment with LY294002 (50 nmol/L) …

2009年3月5日 · To exclude potential bias in sampling, BrdU staining on sequential frozen sections from isolated islets was used for statistical analysis of mitotic cells. The result showed that the …

Immunohistochemical analysis showed a dramatic increase in cyclin D3 expression in several islet cells (Fig. 7 C ) similar to that of BrdU incorporation (Fig. 4) and Ki67 staining (Fig. 5).

13 小时之前 · For analysis of islet endocrine cell proliferation Gpr56 KO and WT mice at postnatal day 9 (P9) were injected intraperitoneally once with 50 mg/kg BrdU and pancreases were …

Consistent with a replicative response, β-cells exhibited BrdU incorporation. Further, Id3 potently repressed expression of the cyclin dependent kinase inhibitor p57Kip2, a gene which is also …

In dispersed islet cells, but not in intact islets or in vivo, pro-proliferative conditions promoted both BrdU and γH2AX labeling, which could indicate DNA damage, DNA replication stress, or cell …