2012年7月22日 · Genetic analysis indicates that BZR1 and PIFs are interdependent in promoting cell elongation in response to BR, darkness or heat. These results show that the BZR1–PIF4 interaction controls a...

Genetic analysis indicates that BZR1 and PIFs are interdependent in promoting cell elongation in response to BR, darkness or heat. These results show that the BZR1-PIF4 interaction controls a core transcription network, enabling plant growth co-regulation by …

2018年12月3日 · The Arabidopsis PIF4 and BES1/BZR1 transcription factors antagonize light signaling by facilitating co-activated expression of a large number of cell wall-loosening and auxin-related genes. While PIF4 directly activates expression of these targets, BES1 and BZR1 activity switch from a repress …

2024年10月13日 · BZR1, a pivotal brassinosteroid (BR) signaling regulator, has been proposed to interact directly with PIF4 to mediate BR and high-temperature responses. This study aimed to elucidate the involvement of OgBZR1 in the thermal activation of …

2018年1月22日 · We found that brassinosteroids act via the transcription factor BRASSINAZOLE RESISTANT 1 (BZR1), which accumulates in the nucleus at high temperature, where it induces expression of growth-promoting genes. Furthermore, we show that at elevated temperature BZR1 binds to the promoter of PIF4, inducing its expression.

2012年7月22日 · PIF4 and BZR1 targets were identified by PIF4 ChIP-Seq and BZR1 ChIP-chip, respectively; PIFs- and BZR1-regulated genes were differentially expressed in pifq versus the wild type and in...

2022年8月4日 · PIF4 and BZR1 exert a balanced regulating of photoreceptor-gene expression, whose products directly or indirectly affect PIF4, HY5, and MYC2 protein stability as a function of light. Growth itself is balanced by both multiple positive and multiple negative feedback on PIF4 and BZR1 activity.

2021年12月1日 · Accumulated PIF4 forms complexes with BRASSINAZOLE RESISTANT1 (BZR1) and BRI1-EMS SUPPRESSOR1 (BES1), which are two well-characterized bHLH proteins in the BR signalling pathway, and coordinately regulates a large number of light- and BR-responsive genes to promote hypocotyl elongation [11, 77].

bzr1 和 pif4 在体外和体内相互作用，与近 2,000 个常见靶基因结合，并协同调节许多这些靶基因，包括促进细胞伸长所需的 pre 家族螺旋-环-螺旋因子。 遗传分析表明，BZR1 和 PIF 在响应 BR、黑暗或热时促进细胞伸长是相互依赖的。

2014年8月1日 · Here we show that the light-regulated PIF4 (phytochrome-interacting factor 4) factor is a phosphorylation target of the BR signaling kinase BRASSINOSTEROID-INSENSITIVE 2 (BIN2), which marks this transcriptional regulator for proteasome degradation.