The C2C12 cell line is a subclone of myoblasts that were originally obtained by Yaffe and Saxel at the Weizmann Institute of Science in Israel in 1977. [1] Developed for in vitro studies of …

The C2C12 cell line differentiates rapidly, forming contractile myotubes and producing characteristic muscle proteins. Treatment with bone morphogenic protein 2 (BMP-2) cause a …

2011年5月17日 · From the C2s the immortal subline C2C12 was selected (Blau et al., 1985). These cells differentiate well into myocytes under appropriate culture conditions given below. …

The C2C12 cell model is a well-established in vitro system used to study muscle cell biology, including myogenesis (muscle formation), gene expression, and muscle metabolism. C2C12 …

Notably, the C2C12 cell model has advantages such as low cost, ease of preparation, and high differentiation potential, making it a widely used model in recent years in exercise medicine …

2022年1月17日 · Intracellular metabolite profiles indicated that C2C12 myotubes cultured in serum and B27 had predominant glycolytic and oxidative metabolism, respectively, indicating …

2024年12月25日 · C2C12 (mouse myoblasts) is a subclone of a mouse myoblast cell line established by D. Yaffe and O. Saxel. C2C12 cells differentiate rapidly, readily forming …

We examined the myofibril biochemical, structural, and biophysical properties of C2C12, a mouse skeletal muscle cell line (American Type Culture Collection), to assess whether force …

Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle. C2C12 cells: biophysical, biochemical, and immunocytochemical properties. C2C12 murine …

When C2C12 cells are infected with the Smad5-adenovirus and stained with an antibody against Smad5, Smad5 is predominantly observed in the cytoplasm (Fig. 2). In contrast, when C2C12 …