2019年8月20日 · We find that C3 protein accumulates in synapses in human AD brains with tau pathology. Furthermore, intact and processed C3 levels are increased in cerebrospinal fluid …

胶质纤维酸性蛋白 (gfap) 是构成 cns 中星形胶质细胞的细胞骨架的一种 iii 类中间纤丝。gfap 建立并维持星形胶质细胞形态，并且对有丝分裂以及神经元-星形胶质细胞通信非常重要。检测 …

2022年3月29日 · Studies have shown that proinflammatory microglia can polarize astrocytes (designated A1 astrocytes) toward a neurotoxic phenotype characterized by increased …

胶质纤维酸性蛋白（Glail fibrillary acidicprotein,GFAP）是一种Ⅲ型中间纤维蛋白,主要存在于成熟的星形胶质细胞内,是星形胶质细胞的重要组成部分,也是主要的细胞骨架，除了在神经系统星 …

2024年3月1日 · Since C3 has been shown to mediate pro-inflammatory responses, we also evaluated the postoperative change in astrocytes and in cytokines after C3 inhibition. Firstly, …

2019年5月22日 · To confirm the differences in C3 protein levels, we performed double staining of C3 and GFAP in brains of another set of terminally sick mice (Fig. 4b). While GFAP …

After pain behavior observation, the expression of glial fibrillary acidic protein (GFAP) in the medullary dorsal horn was observed by immunohistochemistry and immunofluorescence …

一位有远期视神经炎病史的进行性多发性硬化症患者表现出显着的反应性星形胶质细胞增生，内层视网膜中的 c3 表达比未受影响的眼睛更多地延伸到受影响的眼睛的更深层。

2023年10月3日 · 通过相关性分析发现c3的表达水平与多种免疫细胞相关（p<0.05）。在结节性硬化症患者脑组织和血浆中均发现补体c3升高，通过免疫荧光发现补体c3与gfap共定位。在星形 …

First, we show extensive C3 expression in astrocytes (C3 + /GFAP + cells) and significant RGC loss (RBPMS + cells) in post-mortem retinas from people with MS compared to retinas from …