C3a is a 77 residue anaphylatoxin that binds to the C3a receptor (C3aR), a class A G protein-coupled receptor. It plays a large role in the immune response. C3a molecules induce …

Complement activation and inactivation generate the degradation products of complement component 3 (C3; MW: 195 kDa). C3 convertases (C4b2a generated by the classical or lectin …

The complement C3a-C3a receptor Axis regulates epithelial-to-mesenchymal transition by activating the ERK pathway in pancreatic ductal adenocarcinoma. Anticancer Res. 2022 …

C3a formation is common to all three pathways of complement activation: classical (antibody-mediated), lectin and alternative (1, 2). It binds the G-protein coupled C3a receptor (C3aR) on …

2024年9月12日 · Complement C3 (MW: 183 kDa) is one of the most abundant plasma proteins. It is a pivotal component of complement and is central to the activation cascades. The mature …

This antibody, produced in rabbits, specifically targets Complement C3A, a central protein in the complement cascade that plays a crucial role in inflammation and host defense.Validated for …

In this study, with an aim to gain more insights into the function of teleost C3 and C3a, we examined the biological role of Japanese flounder (Paralichthys olivaceus) C3 (PoC3) and …

2019年5月29日 · 检测血清或体液中的c3sp，一般包括c3a、c3c、c3d， 定性方法简便易行， 无需特殊抗血清， 如对流免疫电泳、交叉免疫电泳、免疫固定电泳等；定量方法采用sid、elisa、 …

Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the complement system of vertebrate animals …

Reduced C3a was manually synthesized step-wise on a 0.5 mmol scale in three segments consisting of C3a(1-22)-α-thioester, C3a(23-48)-α-thioester and C3a(49-77). C3a(1-22)-α …