Mouse Monoclonal C4b antibody - conjugated to FITC. Suitable for IHC-Fr and reacts with Human samples. Immunogen corresponding to Native Full Length Protein corresponding to Human C4B.

The Anti-C4d FITC antibody will identify human complement split product C4d. It is suggested to be a valuable marker for humoral rejection of transplants (kidney, heart, lung). The antibody is applicable for detection of cell- or solid-phase bound C4 and C4d split product by flow cytometry using FlowPRA® Class I and II screening test beads ...

View Mouse Monoclonal anti-Complement C4d Antibody (C4D204) [FITC] (NBP2-34581F). Validated Applications: ELISA, ICC/IF, IHC. Validated Species: Human.

FITC Mouse monoclonal [LP69] to C4d; Suitable for: IHC-Fr; Reacts with: Human; Conjugation: FITC. Ex: 493nm, Em: 528nm; Isotype: IgG1

C4d是抗体触发补体通过经典途径活化后C4的裂解产物，能稳定地结合在发生排斥的移植物内皮的表面。 检测C4d作为机体针对同种异体移植物抗体检测的一个间接信号，大量研究表明：C4d是肾移植免疫中的重要标记物，同时也是心脏、肝及其他器官移植免疫检测的 ...

Method: For detection of cell- or solid-phase bound C4d and C4d split product by flow cytometry using FlowPRA® Class I and II screening test beads from One Lambda. Liquid IgG fraction, purified by protein G chromatography. The antibody was conjugated with FITC under optimum conditions. The solution is free of unconjugated FITC.

Invitrogen Anti-Complement C4d Monoclonal (LP69), Catalog # MA5-46581. Tested in Immunohistochemistry (Frozen) (IHC (F)) applications. This antibody reacts with Human samples. Supplied as 50 µg purified antibody (1 mg/mL).

C4d is the degradation product of the activated complement factor C4, a component of the classical complement cascade, which is typically initiated by binding of antibodies to specific target molecules. Detection of C4d is regarded as an indirect sign, a “footprint” of an antibody response against the allograft.

The Anti-Human C4d FITC Antibody identifies human complement split product C4d. It is suggested to be a valuable marker for humoral rejection of transplants Products

C4d 是补体因子C4激活后的裂解片段，是经典补体级联反应的成分，通过抗体与特异性的目标分子 结合而启动。 C4d检测被看做是抗体排斥同种移植反应的间接印证或者印记。 在大多的文献中都将 C4d看做是肾脏，心脏， 肝脏以及其他移植中的重要的指标。 1. 肾小球 C4d 沉积可先于局灶节段性肾小球硬化的发展 van de Lest et al., Kidney Int, 2019; 96 (3):738-749. 2. “肾小球 C4d 沉积可先于 FSGS 的发展，这表明补体激活可能在 FSGS 的发展中发挥致病作用。 ” C4d 在肾移植受 …