Dec 24, 2024 · CA14 (Carbonic Anhydrase 14) is a Protein Coding gene. Diseases associated with CA14 include Intracranial Hypertension, Idiopathic and Mixed Sleep Apnea . Among its related pathways are Metabolism and Reversible hydration of carbon dioxide .

Carbonic anhydrase 14 is an enzyme that in humans is encoded by the CA14 gene. [5] [6] Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and ...

碳酸酐酶14 (ca14)是一个多肽，由一个细胞外n-末端催化结构域、一个跨膜区和一个短的有潜在磷酸化位点的胞内c-末端片段组成。 CA14在脑神经元的胞体和轴突质膜、肝脏的肝细胞质膜上表达，也在肾脏特别是近端小管顶膜上优先表达。

碳酸酐酶 (CA) 是一大类锌金属酶，可催化二氧化碳的可逆水合。 它们参与多种生物过程，包括呼吸、钙化、酸碱平衡、骨吸收以及房水、脑脊液、唾液和胃酸的形成。 它们在组织分布和亚细胞定位方面表现出广泛的多样性。 CA XIV 被预测为 I 型膜蛋白，与其他跨膜 CA 亚型 CA XII 具有最高的序列相似性；然而，它们具有不同的组织特异性表达模式，因此可能发挥不同的生理作用。 [RefSeq 提供，2008 年 7 月] Carbonic anhydrases (CAs) are a large family of zinc …

RNA specificity category based on RNA sequencing data from cancer cell lines in the Human Protein Atlas grouped according to type of cancer. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.

Feb 8, 2025 · Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid.

Sep 17, 2024 · Clinical resource with information about CA14, Biological insights from 108 schizophrenia-associated genetic loci., and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, PharmGKB and clinicaltrials.gov.

碳酸酐酶14是一种酶，在人类中被ca14基因编码。 碳赤霉素（cas）是一大批锌金属酶，可催化二氧化碳可逆水合。他们参与了多种生物学过程，包括呼吸，钙化，酸碱平衡，骨吸收，以及水幽默，脑脊液，唾液和胃酸的形成。

Jan 4, 2025 · Carbonic anhydrase 14 protects the liver against the cytotoxicity of bile acids in a biliary bicarbonate umbrella-related manner. Qian J, et al. Life Sci, 2022 Dec 1. PMID 36302497. Loss of luminal carbonic anhydrase XIV results in decreased biliary bicarbonate output, liver fibrosis, and cholangiocyte proliferation in mice.

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