
The length of uninterrupted CAG repeats in stem regions of repeat ...
2022年12月30日 · Extended CAG trinucleotide repeats (TNR) in the genes huntingtin (HTT) and androgen receptor (AR) are the cause of two progressive neurodegenerative disorders: …
中国男性雄激素受体基因 (CAG)n重复多态性的初步研究
目的研究正常中国男性雄激素受体(androgen receptor, AR)基因(CAG)n重复序列的多态性.方法应用DNA测序基础上的[α-32P]dCTP掺入不对称PCR-变性聚丙烯酰胺凝胶电泳(polyacrylamide gel …
Handedness and the X chromosome: The role of androgen receptor CAG ...
2015年2月9日 · Here, we examined the relationship between the length of the CAG-repeat in AR and different handedness phenotypes in a sample of healthy adults of both sexes (n = 1057). …
Androgen receptor CAG repeat length contraction in diseased
2007年4月17日 · To investigate contraction of CAG repeats within the androgen receptor gene (AR) as shorter CAG repeats have been implicated as a possible risk factor in prostate cancer …
Unexpected frequency of the pathogenic AR CAG repeat …
2023年2月17日 · CAG repeat expansions in the AR gene cause spinal and bulbar muscular atrophy. Zanovello et al. establish a pipeline to detect AR CAG expansion from whole-
Androgen receptor (AR) gene CAG trinucleotide repeat length …
2015年5月1日 · We examined the AR gene CAG repeat length and measures of weight and body mass index (BMI) in 27 non-syndromic obese and 33 lean controls and for the first time …
The androgen receptor CAG repeat: a modifier of carcinogenesis?
2002年7月31日 · The first exon of the human androgen receptor (AR) contains a translated CAG (poly-glutamine) repeat. The repeat length is polymorphic in the normal population ranging …
The CAG repeat within the androgen receptor gene and its ... - PNAS
1997年4月1日 · Cell division in the prostate gland is controlled by the interaction of testosterone and dihydrotestosterone with the androgen receptor (AR) (1). The AR gene contains a …
Unexpected frequency of the pathogenic AR CAG repeat …
2023年7月3日 · CAG repeat expansions in exon 1 of the AR gene on the X chromosome cause spinal and bulbar muscular atrophy, a male-specific progressive neuromuscular disorder …
Significance of the CAG repeat length in the androgen receptor gene (AR ...
The influence of the length of the CAG repeat on the transactivation function of the M780I-mutant AR (causing partial and complete AIS) has been determined by cotransfection of HeLa cells …