
Dynamic 3D imaging of cerebral blood flow in awake mice using …
2023年3月21日 · Here, we report ultrahigh-resolution optical coherence Doppler tomography (µODT) for 3D imaging of CBF velocity (CBFv) dynamics in awake mice by developing self …
Optical manipulation of local cerebral blood flow in the deep …
2021年7月27日 · An artificial tool for manipulating local cerebral blood flow (CBF) is necessary for understanding how CBF controls brain function. Here, we generate vascular optogenetic tools …
Mapping cerebral perfusion in mice under various anesthesia …
2024年2月28日 · In the present work, we developed a hypoxia-induced BOLD-DSC MRI setup for mapping perfusion in mice under volatile anesthesia. We assessed the sensitivity and …
Longitudinal Awake Imaging of Mouse Deep Brain …
2025年2月27日 · In this study, we developed a method for awake and longitudinal ULM brain imaging in a mouse model to eliminate the confounding vascular effects of anesthesia and …
Inhibiting Ca2+ channels in Alzheimer’s disease model mice …
2024年9月18日 · Early in Alzheimer’s disease (AD), pericytes constrict capillaries, increasing their hydraulic resistance and trapping of immune cells and, thus, decreasing cerebral blood flow …
Noninvasive Optical Measurement of Cerebral Blood Flow in Mice …
We propose an optical imaging technique that measures CBF in mice noninvasively through a combined ICG molecular dynamics analysis. To the best of our knowledge, this is the first …
Cerebral blood flow MRI in mice using the cardiac‐spin‐labeling ...
This study demonstrates a practical approach to image quantitative CBF and physiologically evoked CBF changes in mice using the continuous spin labeling technique with a cardiac …
Functional ultrasound imaging reveals microvascular rarefaction ...
5 天之前 · Functional ultrasound (fUS) imaging, an advanced modality offering superior spatiotemporal resolution, was used to evaluate microvascular density, NVC responses, and …
Mapping functional connectivity using cerebral blood flow in the …
2014年12月10日 · Brain function can be assessed from resting-state functional connectivity (rs-fc) maps, most commonly created by analyzing the dynamics of cerebral hemoglobin …
Cerebral blood flow MRI in mice using the cardiac-spin ... - PubMed
Continuous arterial spin labeling MRI with a separate neck labeling coil provides a highly sensitive method to image cerebral blood flow (CBF). In mice, however, this has not been possible …