Chemokine (C-C motif) ligand 21 (CCL21) is a small cytokine belonging to the CC chemokine family. This chemokine is also known as 6Ckine (because it has six conserved cysteine …

2024年12月24日 · CCL21 (C-C Motif Chemokine Ligand 21) is a Protein Coding gene. Diseases associated with CCL21 include Periapical Periodontitis and Scrapie. Among its related …

CCL21，又称 exodus-2、次级淋巴组织趋化因子 (SLC)，属于 CC 趋化因子家族的一种小细胞因子，在人类基因组中位于第 9 号染色体上。 CCL21可以在淋巴管起始处和淋巴器官中组成型表 …

CCL21 promotes immune activity in the tumor microenvironment (TME) by colocalizing dendritic cells (DC) and T cells programing ectopic lymph node architectural structures that correlate …

2021年7月23日 · CCL21 is constitutively expressed by lymphatic endothelial cells and is essential for guiding DCs to the lymph nodes. Two mouse genes encode functional CCL21 variants, …

In autoimmune diseases, CCL21 promotes the adhesion and migration of various immune cells, including T lymphocytes, macrophages, and neutrophils, by high-affinity binding to CCR7. It is …

CCL21/CCR7 prevents apoptosis by upregulating the expression of bcl-2 and by downregulating the expression of bax and caspase-3 potentially via the ERK pathway in non-small cell lung …

CCL21 is a homeostatic lymphoid chemokine instrumental in the recruitment and organization of T cells and dendritic cells into lymphoid T areas. In human secondary lymphoid organs (SLOs), …

趋化因子ccl21属于cc类趋化因子,主要表达于周围淋巴组织.研究表明,ccl21可以促使血管内皮 细胞黏附流动的t细胞参与淋巴细胞归巢,能够很强地趋化t,b淋巴细胞,成熟树突状细胞(dc)及nk细胞, …

It is a high affinity functional ligand for Chemokine Receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible …