
The CD14+/lowCD16+ monocyte subset is more susceptible to
2010年11月4日 · The apoptosis of CD14 +/low CD16 + monocytes was ROS dependent as reducing ROS levels significantly reduced cell death. This is the first report of a differential …
Pro-inflammatory hepatic macrophages generate ROS through …
2017年12月21日 · These data suggested that endocytosis of TLR4–MD2 complex in human CD68 low CD14 high macrophages by palmitate-mediated ROS generation, which might be …
Cell Reports丨CD14在细胞内LPS传感中的独立于TLR4的关键作用
CD14 是一种糖磷脂酰肌醇锚定的质膜蛋白,在 LPS 介导的 TLR4 激活中具有长期确定的作用;CD14 与 LPS 结合并将 LPS 转移到 TLR4-MD2 复合物,从而启动 myddosome 组装和信号 …
Monoclonal Antibody to CD14, TLR4, or CD11b: Impact of Epitope …
In this review, we will discuss known mechanisms underlying the therapeutic efficiency of CD14, TLR4, and CD11b/CD18 antibodies with a focus on LPS-dependent ROS or cytokine …
Monoclonal Antibody to CD14, TLR4, or CD11b: Impact of Epitope …
2020年11月20日 · In this review, we will discuss known mechanisms underlying the therapeutic efficiency of CD14, TLR4, and CD11b/CD18 antibodies with a focus on LPS-dependent ROS …
Human CD14dim monocytes patrol and sense nucleic acids and ... - PubMed
2010年9月24日 · CD14 (dim) monocytes were weak phagocytes and did not produce ROS or cytokines in response to cell-surface Toll-like receptors. Instead, they selectively produced …
Impact of CD14 on Reactive Oxygen Species Production from …
2019年3月3日 · Obtained results suggest that glycosylphosphatidylinositol-anchored CD14 is the key player in LPS-induced PMN priming for fMLP-triggered ROS production. We believe that …
Monoclonal Antibody to CD14, TLR4, or CD11b: Impact of Epitope …
In this review, we will discuss known mechanisms underlying the therapeutic efficiency of CD14, TLR4, and CD11b/CD18 antibodies with a focus on LPS-dependent ROS or cytokine …
Moreover, the consequences of antigenic recognition of CD14, TLR4, or CD11b by specific F(ab′) 2 fragments are not always investigated. In this review, we will discuss known …
Human CD14 dim Monocytes Patrol and Sense Nucleic Acids and …
2010年9月24日 · CD14 dim monocytes were weak phagocytes and did not produce ROS or cytokines in response to cell-surface Toll-like receptors. Instead, they selectively produced …