2024年12月24日 · This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in …

CD166 antigen is a 100-105 kD typeI transmembrane glycoprotein that is a member of the immunoglobulin superfamily of proteins. In humans it is encoded by the ALCAM gene. [5] [6] It is also called CD166 (cluster of differentiation 166), MEMD, [7] SC-1/DM-GRASP/BEN in the chicken, and KG-CAM in the rat.

cd166. alcam. 激活的 t 细胞和 b 细胞、单核细胞、胸腺上皮细胞和神经细胞。 通过结合 cd6 介导细胞粘附，参与神经生长，并可能在 t 细胞和 b 细胞与激活白细胞的结合过程中发挥作用。 cd167a. ddr1. 在大脑、肺部、胎盘以及肾脏中表达水平最高。

2020年1月6日 · cd166 (alcam)：cd166又称cd6配体或活化的白细胞粘附分子(alcam)，属于免疫球蛋白超家族成员，是一种分子量为100-105kd的跨膜糖蛋白。 它表达于活化的t细胞、活化的单核细胞、上皮细胞、成纤维细胞和神经元。alcam/cd6相互作用可能参与t细胞的发育和调节。

2021年10月1日 · Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) is a glycoprotein involved in homotypic and heterotypic cell adhesion. ALCAM can be proteolytically cleaved at the cell surface by metalloproteases, which generate shedding of its ectodomain.

2014年9月15日 · CD166, also known as activated leukocyte cell adhesion molecule (ALCAM), is expressed by various cells in several tissues including cancer. However, the role of CD166 in malignant tumors is controversial, especially in pancreatic cancer. This study aimed to clarify the role and significance of CD166 expression in pancreatic cancer.

2018年3月23日 · CD166, also known as ALCAM (activated leucocyte cell adhesion molecule), was the first endogenous ligand of CD6 to be identified. 12 CD166, a member of the immunoglobulin gene superfamily, is...

This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain.

Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) is a glycoprotein involved in homotypic and heterotypic cell adhesion. ALCAM can be proteolytically cleaved at the cell surface by metalloproteases, which generate shedding of its ectodomain. In various tumors, ALCAM is overexpressed and serve …

白细胞活化黏附因子 （Activated Leukocyte Cell Adhesion Molecule，ALCAM），也被称为 CD166 ，是一种分子量为110kDa的细胞表面糖蛋白，属于免疫球蛋白超家族且是I型膜糖蛋白。白细胞活化黏附因子（ALCAM，Activated Leukocyte Cell Adhesion Molecule）是一种重要的细胞黏 …