1991年6月1日 · In active multiple sclerosis (MS), T cell adhesion to sheep red blood cells (SRBC) is deficient. The CD2 protein mediates adhesion to SRBC. Since ligands that bind CD2 can activate T cells, we studied adhesion and activation through CD2 in leukocytes from MS patients.

In active multiple sclerosis (MS), T cell adhesion to sheep red blood cells (SRBC) is deficient. The CD2 protein mediates adhesion to SRBC. Since ligands that bind CD2 can activate T cells, we studied adhesion and activation through CD2 in leukocytes from MS patients.

2022年8月5日 · After lysing cells in maltoside-containing buffer, OST-tagged CD2 was recovered with Strep-Tactin Sepharose beads, and associated proteins were detected and quantified by mass spectrometry (MS). We identified 68 high-confidence CD2-interacting proteins that showed a greater than threefold enrichment, with a P value below 0.05 in at least two of ...

CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It has also been called T-cell surface antigen T11/Leu-5, LFA-2, [ 5 ] LFA-3 receptor, erythrocyte receptor and rosette receptor.

2006年9月15日 · Based on concordant gene expression signatures, predominantly driven by recurrent translocations and hyperdiploidy, MM could be characterized as belonging to 7 distinct molecular entities. HY, CD-1, CD-2, and LB subgroups were associated with superior event-free and overall survival following high-dose therapy and stem cell transplantation.

2023年6月7日 · 我的方向是多孔材料（MOF、COF）吸附VOCs（苯、乙苯、苯乙烯等），目前我的想法是，通过gaussian计算吸附剂和吸附质的各个原子的电荷，然后在MS里通过设置力场和计算得到的电荷做吸附。

CD2 MicroBeads were developed for the positive selection or depletion of CD2 + cells from human PBMCs. CD2 is expressed on all T cells and most NK cells. The CD2 antigen is a 50 kDa single-chain transmembrane glycoprotein, also known as …

2023年6月15日 · Using patient-derived co-cultures, humanized mouse models, and single-cell RNA-sequencing of patient melanomas biopsied before and on immune checkpoint blockade, we find that intact cancer cell-intrinsic expression of CD58 and ligation to CD2 is required for anti-tumor immunity and is predictive of treatment response.

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