CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels.

This review summarizes recent data on CD23, a low affinity receptor for IgE (Fc epsilon RII). CD23 is the only FcR which does not belong to the immunoglobulin gene superfamily. The …

2024年3月21日 · cd23是一种低亲和力ige受体，是一种c型凝集素，在调节ige产生，b细胞分化，免疫细胞激活以及过敏反应调节中扮演着重要角色，是过敏疾病治疗的潜在靶点。

2016年5月16日 · To understand the molecular mechanism by which CD23 negatively regulates BCR-mediated B-cell activation, we examined the relative expression levels of CD23 in …

CD23/FcεRII, the low-affinity receptor for IgE, is constitutively expressed on B cells and has been shown to regulate immune responses. Simultaneous binding of IgE to FcεRI and CD23 is …

2020年12月30日 · While evidence from experimental disease models as well as allergic patient studies on CD23 is still lacking, evidence shows that i) CD23 can absorb and clear IgE from …

2024年8月21日 · CD23是一种种低亲和力IgE受体，在调节IgE产生和B细胞分化中具有重要作用。 在B细胞上中，启动IgE依赖性抗原摄取并呈递给T细胞。 在巨噬细胞中， IgE 结合和抗原交联 …

The association of immunoglobulin E (IgE) with allergic diseases and asthma is well established. IgE binds to two receptors on various immune and inflammatory cells. The lower-affinity IgE Fc …

CD23 is the low-affinity receptor for immunoglobulin (Ig)E and plays important roles in the regulation of IgE responses. CD23 can be cleaved from cell surfaces to yield a range of …

39.5.2.2 CD23 (FcεRII): The Low-affinity Receptor for IgE. CD23 is a type II integral membrane protein with an extracellular C-terminal domain that is homologous to C-type lectins.