Cysteine-specific 89Zr-labeled anti-CD25 IgG allows immuno-PET …
2022年12月15日 · We prepared 89 Zr-anti-CD25 IgG specifically labeled to sulfhydryl moieties by maleimide-deferoxamine conjugation. CD25 (+) SUDHL1 human T-cell lymphoma cells …
人 CD 抗原完全指南 - Abcam中文官网
与 cd25、cd122、cd124、cd127 等其他细胞表面蛋白形成复合物，复合物再与其他细胞表面蛋白形成细胞因子 il2、il4、il7、il9 和 il15 的受体。通过含 cd132 的复合物发挥作用，上述细胞因 …
免疫治疗新突破：CD25（IL2RA）——调控Tregs的核心靶点与临 …
CD4+CD25+Tregs具有两大核心功能特性：一是免疫无能性，即不响应IL-2等刺激；二是免疫抑制性，可以抑制效应T细胞增殖，并影响其细胞因子产生（图1） [2-6]。 图1. CD25参与Tregs调 …
【靶点Talk】CD25：肿瘤免疫疗法新势力 - 知乎 - 知乎专栏
人源化抗cd25单体注射液 健尼哌 （三生国健研发）适应症为预防肾移植引起的急性排斥反应。健尼哌通过与cd25结合，抑制il-2与受体结合所介导的t细胞增殖。 cd25抗体和pd-1抗体的联合 …
CD25 targeting with the afucosylated human IgG1 antibody …
2023年5月2日 · Ex vivo treatment of primary AML patient samples with CD25 Mab, a human CD25 specific glycoengineered IgG1 antibody led to the specific killing of two different cell …
锆[89Zr]-CD25 IgG(89Zr-CD25 IgG) - 药物靶点：IL2RA_在研适应 …
The interleukin-2 receptor α chain (IL-2Rα; CD25) is a promising target for immune therapy and radioimmunotherapy of lymphomas. Immuno-PET could facilitate this approach by visualizing …
The Effect of Antibody Fragments on CD25 Targeted Regulatory T …
CD25-targeted NIR-PIT has been shown to induce spatially selective depletion of tumor-associated Treg cells. In this study, we compared the efficacy of an antibody fragment, anti …
Cysteine-specific 89Zr-labeled anti-CD25 IgG allows immuno-PET …
2022年12月15日 · CD25(+) SUDHL1 human T-cell lymphoma cells showed high anti-human 89 Zr-CD25 IgG binding that reached 32-fold of that of CD25(-) human lymphoma cells and was …
A study of circulating anti-CD25 antibodies in non-small cell …
Results: Mann-Whitney U test showed that the anti-CD25 IgG level was significantly higher in patients with NSCLC than control subjects (Z = -7.48, P < 0.001) while the anti-CD25 IgA level …
Further study of circulating IgG antibodies to CD25‐derived …
2016年2月16日 · In brief, both the CD25‐derived peptide antigen and control antigen were synthesized by solid‐phase chemistry with a purity of > 95%, and then applied to develop a …