
LCP1 Gene - GeneCards | PLSL Protein | PLSL Antibody
2024年12月25日 · Phosphorylated on a serine residue in response to costimulation through TCR/CD3 and CD2 or CD28. Serine phosphorylation promotes association with the actin …
LCP1 蛋白, Human (P.pastoris, His) - MCE
LCP1 蛋白是一种肌动蛋白结合调节因子,在 T 细胞激活中发挥着至关重要的作用,通过 TCR/CD3 和 CD2 或 CD28 响应共刺激信号。 它调节 IL2RA/CD25 和 CD69 的细胞表面表达, …
lcp1 - Abcam
Relocalizes to the immunological synapse between peripheral blood T-lymphocytes and antibody-presenting cells in response to costimulation through TCR/CD3 and CD2 or CD28 …
Cancer Cell | 南开大学院士团队揭示靶向CD28/PD-L1促进三阴性乳 …
近日,南开大学免疫研究所的 曹雪涛 院士团队在《Cancer Cell》(IF 48.8)杂志上发表了题为 “Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti …
靶点梳理丨CD28卷土重来 - 知乎专栏
CD28是PD-1疗法有效杀死癌细胞和消除小鼠慢性病毒感染的必要条件。 对PD-1疗法有反应的肺癌患者有更多的CD28+T细胞,这表明CD28可能预测治疗反应。 2019年11月,赛诺菲在Nature …
淋巴细胞胞质蛋白 1(LCP1)基因 | MCE
Plastin 1 (也称为 Fimbrin) 是第三种不同的 Plastin 亚型,它在小肠中以高水平特异性表达。 L 同种型仅在造血细胞谱系中表达,而 T 同种型已在具有复制潜力的实体组织的所有其他正常细胞 ( …
《癌细胞》:南开大学团队揭示乳腺癌细胞“化用”共刺激分子CD28…
流式细胞术分析显示,敲除TNBC细胞Cd28导致的肿瘤微环境重塑,代表性特征是CD8+T细胞以及1型经典树突状细胞(cDC1s)的数量和占比上升,且CD8+T细胞的 IFN-γ 、 颗粒酶B 和 穿 …
LCP1 Antibody - Cell Signaling Technology
4 天之前 · LCP1 becomes phosphorylated at Ser5 upon stimulation through the T cell receptor/CD3 complex in association with the CD2 cell adhesion molecule or the CD28 …
LCP1 | definition of LCP1 by Medical dictionary
A gene on chromosome 13q14.3 that encodes L-plastin/lymphocyte cytosolic protein 1, an actin-binding protein expressed only in haemopoietic cells. It plays a role in activating T-cells in …
Lcp1 - lymphocyte cytosolic protein 1 基因 | MCE
Enables actin filament binding activity and identical protein binding activity. Acts upstream of or within actin filament bundle assembly. Located in several cellular components, including actin …