2020年11月30日 · The role of CD38 in immune cells ranges from modulating cell differentiation to effector functions during inflammation, where CD38 may regulate cell recruitment, cytokine …

2020年11月29日 · CD38 is a protein of 300 amino acids encoded by homologous genes located on chromosome 4 and 5 in humans and mice, respectively (15). Within the cell, CD38 is often …

2024年12月24日 · CD38 (CD38 Molecule) is a Protein Coding gene. Diseases associated with CD38 include Prolymphocytic Leukemia and Leukemia, Chronic Lymphocytic 2. Among its …

2003年9月15日 · In chronic lymphocytic leukemia (CLL), expression of CD38 signifies a poor prognosis, though it does not correlate precisely with the presence of unmutated …

2023年5月18日 · CD38 is highly expressed on most multiple myeloma cells; the anti-CD38 monoclonal antibody daratumumab is used therapeutically in multiple myeloma patients and …

Cluster of differentiation 38 (CD38) is a cell surface glycoprotein and multifunctional extracellular enzyme. As a NADase, CD38 produces adenosine through the adenosine energy pathway to …

CD38 is a multifunctional protein widely expressed in cells from the immune system and as a soluble form in biological fluids. CD38 expression is up-regulated by an array of inflammatory …

CD38 is a novel multifunctional protein that serves not only as an antigen but also as an enzyme. It catalyzes the metabolism of cyclic ADP-ribose and nicotinic acid adenine dinucleotide …

2025年2月8日 · Data suggest CD38 (CD38 antigen (p45) protein) and CD49d (alpha4 Integrin; very late antigen-4 alpha) are more than just markers of an aggressive chronic lymphocytic …

In this paper, we reviewed the role and mechanism of CD38 + CD4 + T cells / CD38 + CD8 + T cells in cellular immunity and the effects of the CD38-NAD + axis on T cell activity.