2024年7月30日 · CD55，即衰变加速因子（Decay Accelerating Factor, DAF），是一种高度保守的细胞膜表面糖蛋白，属于补体调节蛋白（CRP）家族的重要成员。 它不仅在维持机体免疫稳态中扮演着关键角色，还深刻影响着肿瘤的发生、发展和转移过程。

2024年4月24日 · CD55, or decay accelerating factor, is a membrane lipid microdomain-associated, GPI-anchored protein implicated in the shielding of cells from complement-mediated attack via accelerating decay of C3 and C5. Loss of CD55 is associated with a number of pathologies due to hyperactivation of the complement system.

2023年7月13日 · CD55和CD97重组蛋白是免疫学中研究配体相互作用、功能特性和发现潜在治疗靶点的重要工具。Izuhara及其同事使用人CD55重组蛋白进行实验，以确认其对猫抗CD55抗体的特异性。该实验猫抗CD55抗体与人CD55蛋白（ 义翘神州 ）混合，该混合溶液被用作一抗。结果无 …

We will review the expression of CRPs in cancer, focussing on CD55 and highlight other roles of the CRPs and their involvement in leukocyte function. We will also provide some data providing a potential mechanism by which soluble CD55 can inhibit T-cell function and discuss some of the implications of this data.

2024年7月1日 · CD55, also known as decay-accelerating factor (DAF) can modulate the activation of complement through inhibiting the formation of complement 3 convertase and its dysregulation is involved in various inflammatory diseases.

2024年12月24日 · CD55 (CD55 Molecule (Cromer Blood Group)) is a Protein Coding gene. Diseases associated with CD55 include Complement Hyperactivation, Angiopathic Thrombosis, And Protein-Losing Enteropathy and Blood Group, Cromer System. Among its related pathways are Transport to the Golgi and subsequent modification and Complement cascade.

2024年11月5日 · CD55和CD97重组蛋白是免疫学中研究配体相互作用、功能特性和发现潜在治疗靶点的重要工具。Izuhara及其同事使用人CD55重组蛋白进行实验，以确认其对猫抗CD55抗体的特异性。该实验猫抗CD55抗体与人CD55蛋白（义翘神州）混合，该混合溶液被用作一抗。结果无蛋 …

This 70-75 kDa glycoprotein CD55 containing four SCR modules is involved in the regulation of the complement cascade. It inhibits complement activation by suppressing the function of C3/C5 convertases, thereby limiting local generation or deposition of C3a/C5a and membrane attack complex (MAC or C5b-9) production.

2024年4月24日 · CD55是一种重要的调节蛋白，它在多种细胞类型中表达，并在免疫系统的调节、防止病理性自身免疫和炎症反应中发挥作用。 CD55的表达分布主要包括以下细胞类型，内皮细胞，上皮细胞，免疫细胞，红细胞和其他细胞中。 CD55的表达分布和功能在维持机体免疫平衡和健康中具有重要意义。 （数据来源：uniprot） CD55结构及配体CD97. CD55属于膜蛋白，通过糖基磷脂酰肌醇（GPI）基团固定在膜上，CD55蛋白具有C端糖基磷脂酰肌醇锚、O-糖基化丝氨 …

2022年12月28日 · CD55, or decay accelerating factor, is a membrane lipid microdomain-associated, GPI-anchored protein implicated in the shielding of cells from complement-mediated attack via accelerating decay of C3 and C5. Loss of CD55 is associated with a number of pathologies due to hyperactivation of the complement system.