Context: CD79b is a relatively newly characterized B-cell marker that is expressed in a minority of chronic lymphocytic leukemia (CLL) cases. Objective: To systematically correlate CD79b …

The surface expression of CD79b, using the monoclonal antibody (Mab) CB3-1, on B lymphocytes from normal individuals and patients with B cell chronic lymphocytic leukemia (CLL) has been …

We evaluated anti-CD79b for its usefulness in the diagnosis of B-cell chronic lymphoproliferative disorders (BCLPDs), particularly chronic lymphocytic leukemia (CLL) and mantle cell …

2008年11月16日 · High CD79b expression has been associated with atypical morphology, strong expression of surface Ig, advanced clinical stage and short overall survival in B-CLL (Garcia …

2019年11月13日 · Chronic lymphocytic leukemia (CLL) demonstrates dim surface staining of CD79b compared to normal B cells or other B cell malignancies, in part due to overexpression …

In our study we tested levels and expression patterns of common B cell markers CD20, CD22 and CD79b in order to determine differences of these parameters in the peripheral blood samples …

We explored the mechanism for IgM surface expression by CRISPR/Cas9-induced deletion of CD79A or CD79B in four B-lymphoma cell lines. Deletion of either CD79 protein caused loss …

the expression of CD79b in CLL, to estimate quantitatively the number of molecules per cell, and finally to explore if this antigen could be used in the detection of MRD by flow cyto-

2000年4月15日 · Because immunoglobulin (Ig)-β (CD79b) is required for immunoglobulin allelic exclusion, we examined the CD79b expressed by four chronic lymphocytic leukemia (CLL) …

2000年5月5日 · Loss of expression and mutations in the critical BCR protein B29 (Igβ, CD79b), are prevalent in CLL and could produce the hallmark features of these leukemic B cells. …