CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR …

Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine …

CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR …

CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation.

The CD8 antibody, clone SK1, is derived from hybridization of mouse NS-1 myeloma cells with spleen cells from BALB/c mice immunized with human peripheral blood T lymphocytes. The …

This tandem fluorochrome is comprised of a Allophycocyanin (APC) donor that has excitation maxima (Ex Max) of 651 nm and an acceptor dye, Cy™7, with an emission maximum (Em …

CD8 plays important roles in T cell activation and selection. The extracellular IgSF domain of CD8α binds to a non-polymorphic determinant on HLA class I molecules (α3 domain) and …

CD8也称为T8或Leu2，是免疫球蛋白超家族的一员，表达于大部分胸腺细胞、外周血T细胞亚群和NK细胞 (基本为CD8α/α同源二聚体)。 CD8在抗原识别和T细胞活化中，作为MHC I类分子受 …

Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine …

APC通过MHC-I向CD8+T细胞呈递抗原肽 所有有核的细胞都有MHC-I，这些细胞均可以通过 蛋白酶体 降解胞内的蛋白质，部分蛋白质经过加工交给MHC-I; 类似一个工厂抽检环节；如果此时 …