2024年12月24日 · CDH2 (Cadherin 2) is a Protein Coding gene. Diseases associated with CDH2 include Agenesis Of Corpus Callosum, Cardiac, Ocular, And Genital Syndrome and Attention Deficit-Hyperactivity Disorder 8. Among its related pathways are Cell junction organization and Blood-Brain Barrier: Anatomy.

Cadherin-2 is a transmembrane protein expressed in multiple tissues and functions to mediate cell–cell adhesion. In cardiac muscle, Cadherin-2 is an integral component in adherens junctions residing at intercalated discs, which function to mechanically and electrically couple adjacent cardiomyocytes.

N-cadherin也叫做神经钙黏蛋白（Neural-cadherin/Cadherin-2），是一种钙依赖的单链跨膜糖蛋白，介导细胞的同型和异型粘附。 N-cadherin由疏水跨膜区、细胞外区和高度保守的c端细胞内 …

Yeruva等人以CDH2（N-Cadherin）重组蛋白（购自义翘神州，货号： 11039-H03H）进行免疫染色解离、WB免疫印迹等分析，结果发现 致心律失常性心肌病 （AC）患者自身抗体对CDH2和DSG2具有催化活性，减少粘附分子间的相互作用。

CDH2 belongs to the classic cadherin family of Ca2+-dependent cell adhesion molecules with a meticulously described dual role in cell adhesion and β-catenin signaling. During CNS development, CDH2 is involved in a wide range of processes including ...

该基因编码经典的钙粘蛋白和钙粘蛋白超家族的成员。 可变剪接导致多个转录变体，其中至少一个编码前原蛋白的变体经过蛋白水解处理以产生钙依赖性细胞粘附分子和糖蛋白。 这种蛋白质在左右不对称的建立、神经系统的发育以及软骨和骨骼的形成中发挥作用。 [RefSeq 提供，2015 年 11 月] This gene encodes a classical cadherin and member of the cadherin superfamily.

2025年1月4日 · Gene target information for CDH2 - cadherin 2 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

2015年9月30日 · Western blot analysis and co-immunoprecipitation assays revealed that Cdh2 stabilizes FGFR1 in mEpiSCs. Furthermore, stable transfection of mESCs with Cdh2 cDNA followed by FGF2 supplementation...

The CDH2 gene encodes N (neuronal)-cadherin, which has an essential role in the early steps of brain morphogenesis (summary by Halperin et al., 2021).

2022年9月23日 · CDH2 belongs to the classic cadherin family of Ca²⁺-dependent cell adhesion molecules with a meticulously described dual role in cell adhesion and β-catenin signaling. During CNS development, CDH2 is involved in a wide range of processes including maintenance of neuroepithelial integrity, …