The Cdk8 kinase module regulates interaction of the mediator …
The Cdk8 kinase module (CKM) is a dissociable part of the coactivator complex mediator, which regulates gene transcription by RNA polymerase II. The CKM has both negative and positive …
Structure and noncanonical Cdk8 activation mechanism within …
The Cdk8 kinase module (CKM) in Mediator, comprising Med13, Med12, CycC, and Cdk8, regulates RNA polymerase II transcription through kinase-dependent and -independent …
Molecular and in vivo Functions of the CDK8 and CDK19 Kinase …
2019年1月13日 · CDK8 and its paralog, CDK19, collectively termed ‘Mediator Kinase,’ are cyclin-dependent kinases that have been implicated as key rheostats in cellular homeostasis and …
CDK8 Gene - GeneCards | CDK8 Protein | CDK8 Antibody
2024年12月24日 · CDK8 (Cyclin Dependent Kinase 8) is a Protein Coding gene. Diseases associated with CDK8 include Intellectual Developmental Disorder With Hypotonia And …
Salt stress activates the CDK8-AHL10-SUVH2/9 module to
6 天之前 · The CDK8-AHL10-SUVH2/9 module is critical for transcriptional dynamics in response to salt stress. Salt stress has devastating effects on agriculture, yet the key regulators …
Molecular and in vivo Functions of the CDK8 and CDK19 Kinase Modules
2019年1月14日 · CDK8 and CDK19 are incorporated, in a mutually exclusive manner, as part of a 4-protein complex called the Mediator kinase module. This module reversibly associates with …
The CDK8 Kinase Module: A novel player in the transcription of
The Cdk8 kinase module (CKM) of the Mediator complex modulates the transcriptional response to various stresses. Its involvement in regulating translational machinery has yet to be …
A conserved Mediator–CDK8 kinase module association
2013年4月7日 · The CDK8 kinase module (CKM) is a conserved, dissociable Mediator subcomplex whose component subunits were genetically linked to the RNA polymerase II …
Regulatory functions of the Mediator kinases CDK8 and CDK19
The CDK8 kinase exists in a 600 kDa complex known as the CDK8 module, which consists of four proteins (CDK8, CCNC, MED12, MED13). The CDK8 module associates with regulatory sites …
Structure and noncanonical Cdk8 activation mechanism within an ...
2021年1月15日 · The Cdk8 kinase module (CKM) in Mediator, comprising Med13, Med12, CycC, and Cdk8, regulates RNA polymerase II transcription through kinase-dependent and …
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