Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) also known as CD66e (C luster of D ifferentiation 66e), is a member of the carcinoembryonic antigen (CEA) gene family.

4 天之前 · The drug, which targets carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) on tumour cells, was unable to improve progression-free survival in the CARMEN-LC03 trial in previously...

2024年12月24日 · Complete information for CEACAM5 gene (Protein Coding), CEA Cell Adhesion Molecule 5, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium

2023年11月29日 · Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is a glycosylated cell surface protein that rarely expressed in normal adult tissues but overexpressed in diverse...

CEACAM5 overexpression is a reliable characteristic of CD133-positive colorectal cancer stem cells. A novel model for extrapleural cavity metastasis assessment in patients with lung cancer.

Here we identified that the antigen of MGd1 is CEACAM5, and used MGd1 to investigate the expression of CEACAM5 in non-GC and GC tissues (N=643), as a biomarker for prewarning and prognosis.

Objective: To detect the expression of CEA-related cell adhesion molecule 5 (CEACAM5) in non-small-cell lung cancer (NSCLC) and explore its function in the progression and development of NSCLC. Methods: qRT-PCR and immunohistochemistry were performed to detect CEACAM5 expression in human NSCLC tissues and cell lines.

2023年9月19日 · Human carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5), initially discovered in colon cancer by Gold and Freeman in 1965 [1] [2], has long served as a pivotal tumor marker for clinical detection and diagnosis of colorectal cancer.

In the mid-1960s, CEA was identified as a prominent tumor-associated antigen in human colon cancer [7]. CEA is the product of the CEACAM5 gene and is characterized by having seven extracellular Ig domains and a glycosyl-phosphatidylinositol (GPI) anchor.

2025年1月4日 · Differential expression of carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5) and dipeptidyl peptidase-4 (DPP4) with detection of Middle East respiratory syndrome-coronavirus in peripheral blood.