CEBPA - 维基百科，自由的百科全书
cebpa基因的突变已被证明在急性骨髓性白血病患者的白血病发生和预后中起关键作用。在最近的研究中，在7%到15%的急性骨髓性白血病患者中发现了cebpa突变。
CEBPA - Wikipedia
CCAAT/enhancer-binding protein alpha, the transcription factor that is encoded by CEBPA, is very important in the differentiation of immature granulocytes. Mutation of the CEBPA gene has …
CEBPA Gene - GeneCards | CEBPA Protein | CEBPA Antibody
2024年12月24日 · CEBPA is an intronless gene that is required for granulocyte formation in mice. N-terminal nonsense mutations result in a dominant negative C/EBP-alpha protein while C …
CEBPA gene - MedlinePlus
The CEBPA gene provides instructions for making a protein called CCAAT enhancer-binding protein alpha. This protein is a transcription factor, which means that it attaches (binds) to …
Science Advances丨叶丹团队揭示CEBPA是DNMT3A的特异性抑制 …
2022年1月28日 · cebpa是在粒细胞分化过程中起关键作用在转录因子。 在AML中CEBPA突变率为7~11%，并且CEBPA突变AML患者基因组DNA存在CpG高甲基化现象【4】。 通过筛选 …
CEBPA双突变急性髓系白血病预后再分层研究进展 - 中国医学前沿 …
CCAAT增强子结合蛋白A (CCAAT enhancer binding protein A， CEBPA)基因突变是急性髓系白血病 (acute myeloid leukemia，AML)常见基因突变之一，可分为单突变与双突变。 CEBPA 双 …
CEBPA phase separation links transcriptional activity and 3D …
Here we present evidence that the lineage-instructive TF CEBPA drives extensive chromatin compartment switching and promotes the formation of long-range chromatin hubs during …
CEBPA CCAAT enhancer binding protein alpha [ (human)]
Gene ID: 1050, updated on 8-Feb-2025. This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the …
CCAAT 增强子结合蛋白α（CEBPA）基因 | MCE - MCE-生物活性 ...
CCAAT 增强子结合蛋白α： 这种无内含子的基因编码的转录因子包含一个基本的亮氨酸拉链 (bZIP) 结构域，并识别目标基因启动子中的 CCAAT 基序。 编码的蛋白质在同源二聚体和具有 …
The regulatory control of Cebpa enhancers and silencers in the
2019年6月10日 · Cebpa encodes a transcription factor (TF) that plays an instructive role in the development of multiple myeloid lineages. The expression of Cebpa itself is finely modulated, …