2014年4月28日 · In CED, a cannula (needle) is inserted directly into the parenchyma, and drug infusate is delivered at controlled flow rates into the extracellular space. With convection …

Fluid flow back along the outer surface of a needle (backflow) can be a significant problem during the direct infusion of drugs into brain tissues for procedures such as convection-enhanced …

2014年4月28日 · Flow back along a needle track (backflow) can be a problem during direct infusion, e.g. convection-enhanced delivery (CED), of drugs into soft tissues such as brain. In …

2014年11月11日 · Convection-enhanced delivery (CED) infuses drugs directly into brain tissue. Needle insertion is required and results in tissue damage which can promote flowback along …

2014年4月28日 · In this study, the effect of needle insertion speed on local tissue injury and backflow was evaluated in vivo in the rat brain. Needles were introduced at three insertion …

Convection-enhanced delivery (CED) is a technique to deliver therapeutic macromolecules directly to the CNS and bypass the BBB [3]. In CED, a cannula (needle) is inserted directly into …

2014年4月28日 · In this study, the effect of needle insertion speed on local tissue injury and backflow was evaluated in vivo in the rat brain. Needles were introduced at three insertion …

In this study, the effect of needle insertion speed on local tissue injury and backflow was evaluated in vivo in the rat brain. Needles were introduced at three insertion speeds (0.2, 2, …

2012年4月1日 · Convection Enhanced Delivery (CED) is a technique where a needle is implanted into tissue and a constant flow rate or pressure is applied to deliver infusate...

2014年11月30日 · Convection enhanced delivery (CED) infuses drugs directly into brain tissue. Needle insertion is required and results in tissue damage which can promote flowback along …