CFU-GEMM is a colony forming unit that generates myeloid cells. CFU-GEMM cells are the oligopotential progenitor cells [1] [2] for myeloid cells; they are thus also called common myeloid progenitor cells or myeloid stem cells. "GEMM" stands for granulocyte, erythrocyte, monocyte, megakaryocyte. [3]

CFU-GEMM (Colony-forming unit − granulocyte, erythroid, macrophage, megakaryocyte) • A colony containing both erythroid (hemoglobinized) cells and 20 or more non-erythroid (not hemoglobinized) cells, i.e. granulocytes, macrophages, and/or megakaryocytes • Typically has erythroid cells in the center and non-erythroid cells

1993年2月15日 · The results show that human CFU-GEMM-derived colonies have high replating capability with generation of numerous large secondary CFU-GEMM-colonies, an effect enhanced by CB plasma. This suggests at least a degree of sternness for human CFU-GEMM.

CFU-Blast是早期的造血细胞(CFC-Blast)在体外适当的条件下半固体培养18〜32d后，形成的由形态上未分化的细胞组成的小集落(＞25个细胞)。 这种形态上未分化的细胞具有高度再克隆能力和自我更新潜能，并有产生多系定向祖细胞的能力，在分化程度上相当于HPP-CFC或更 ...

CFU-GEMM：集落形成单位-粒细胞、红细胞、巨噬细胞、巨核细胞。 CFU-GEM是一种多潜能的祖细胞，需要EPO和两种或更多的细胞因子来支持击落的生长以及形成集落内特定谱系子细胞的生长和分化。 由于它们的原始性质，CFU-GEMM倾向于产生大量的>500个细胞的大型集落，其中含有红细胞和可识别的至少两种其它谱系细胞。 来自CFU-GEMM的集落有一个高度密集的核，核和周围细胞之间的边界不清楚。 集落周围可见红细胞簇。 单核细胞和粒细胞细胞 (CFU-GM)易 …

cfu-gemm、cfu-emm、cfu-gem、cfu-gmm等为多向性祖细胞，培养形成的集落含至少三个细胞系的细胞。 每个集落的所有各系细胞源自一个早期祖细胞。 这些早期祖细胞尚有较低的自我更新活力。

CFU-GEMM, multipotent progenitor cells, give rise to erythroid, granulocyte-macrophage and megakaryocytic cells. We have examined the utility of this assay for predicting hematologic recovery in patients treated with high-dose chemotherapy and autologous marrow rescue with cryopreserved marrow.

2019年4月28日 · CFU（集落形成单位）检测是对造血干细胞与祖细胞（HSPCs）分析最为广泛使用的方法之一。 CFU 检测可以量化一个样品中个别细胞的增殖以及分化能力。 这些细胞的潜能可以通过观察由每个接种的祖细胞所产生的集落（更多分化的细胞所组成）来衡量。 大约 14 天的培养足以使集落生长到允许准确计数和鉴定的大小，尽管在某些情况下培养时间可以更短。 此前，我们介绍了与 CFU 检测相关的主题，比如使用 HetaSep™ 富集的造血细胞样本的合适的铺板密 …

CFU-GM is the progenitor cell for GM and gives rise to single lineage-committed progenitors, CFU-G and CFU-M, under the influence of colony-stimulating factors such as GM-CSF, G-CSF, and M-CSF (Metcalf and Burgess, 1982). The biological process of generation of megakaryocytes and platelets is known as megakaryocytopoiesis.

1993年2月15日 · The replating capability of human umbilical cord blood (CB) multipotential (CFU-GEMM) progenitors was assessed in vitro as an estimate of self-renewal using erythropoietin (Epo), steel factor (SLF), and either fetal bovine serum (FBS) or CB plasma.