Though noticeable technological advances related to hemodialysis (HD) have been made, unfortunately, the survival rate of dialysis patients has yet to improve significantly. However, recent research findings reveal that online hemodiafiltration (HDF) significantly improves patient survival in comparison to conventional HD.

HDF represents the most efficient technique in the replacement of renal function by dialysis. High convective fluxes have been correlated with positive clinical outcomes. However, there are technical barriers in performing effective convective therapies 12

Post-dilution HDF: The substitution fluid is infused downstream of the dialyzer into the venous side of the extracorporeal circuit. Post-dilution HDF offers high convective clearances and removal rates of soluble uremic toxins at normal or higher blood flow rates.

2016年9月7日 · Haemodiafiltration (HDF) is a renal replacement modality that combines diffusion and enhanced convection in order to remove small- and middle-molecular-weight compounds, respectively.

In the late seventies, convective-based therapies (i.e., Hemofiltration (HF), Hemodiafiltration (HDF) were recognized for their potential clinical benefits (i.e., reduce intradialytic hypotension, improve dialysis tolerance) and increased efficiency on solute removal (i.e., increased removal of middle-sized uremic compounds) compared to ...

Hemodiafiltration (HDF) is an extracorporeal renal-replacement technique using a highly permeable membrane, in which diffusion and convection are conveniently combined to enhance solute removal in a wide spectrum of molecular weights.

Haemodiafiltration (HDF) is the blood purification therapy of choice for those who want significant removal of uraemic solutes beyond the traditional range of small molecules. Combining diffusive and convective solute transport, a HDF treatment ...

2021年3月31日 · Conventional haemodialysis (HD) is a widely used therapy for the replacement of renal function in children with end-stage kidney disease (ESKD). HD is based on diffusive transport of solutes across a semipermeable membrane and is effective in removing small uraemic retention solutes, such as urea, and correcting electrolyte and fluid imbalances.

2015年11月6日 · Hence, just performing post-dilution online HDF does not automatically result in high convection volumes. In this chapter, not only determinants of convection volume will be discussed, but also several practical and technical issues when aiming for high volume HDF.

2017年12月20日 · Hemodiafiltration (HDF) which combines convection with diffusion could enhance both large and protein-bound uremic toxin removal. Recently, there have been several randomized controlled trials demonstrating that high-efficiency post-dilution online HDF could improve survival.