Calcium and integrin-binding protein 1 is a protein that in humans is encoded by the CIB1 gene and is located in Chromosome 15. [5][6][7] The protein encoded by this gene is a member of the calcium-binding protein family.

Calcium- and integrin-binding protein 1 (CIB1) is a small, ubiquitously expressed protein that was first identified as an intracellular binding partner of a platelet-specific α-integrin cytoplasmic tail.

2024年12月24日 · CIB1 (Calcium And Integrin Binding 1) is a Protein Coding gene. Diseases associated with CIB1 include Epidermodysplasia Verruciformis 3 and Inherited Epidermodysplasia Verruciformis. Among its related pathways are MAPK-Erk Pathway and Development Angiotensin activation of ERK.

CIB1 (calcium and integrin binding1, also called calmyrin) is a 22kDa protein containing two functional EF hand domains at its C-terminus, which bind calcium at physiological concentrations [65]. You might find these chapters and articles relevant to this topic. Yan Yu, ... Lixin Du.

2018年8月20日 · The Arabidopsis genome encodes at least two cryptochromes, cryptochrome 1 (CRY1) and CRY2. The major function of CRY1 is to mediate blue light‐dependent de‐etiolation responses 6, whereas the primary role of Arabidopsis CRY2 is the photoperiodic regulation of floral initiation 7.

2017年10月11日 · Calcium and integrin-binding protein 1 (CIB1) is an EF-hand calcium binding protein, which is involved in many cellular processes, including calcium signaling, cell survival and proliferation, cell migration, cell adhesion and apoptosis.

The early somatic blastomeres founding the tissues in the C. elegans embryo are derived in a stem-cell-like lineage from the P cells. We have isolated maternal effect lethal mutations defining the gene cib-1 in which the P cells, P1-P3, skip a cell …

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Differences in structure, oligomeric state, and phylogeny define a new family of CIB1-related proteins that extends from arthropods to humans. CIB1 (CIB) is an EF-hand-containing protein that binds multiple effector proteins, including the platelet αIIbβ3 integrin and several serine/threonine kinases and potentially modulates their function.

Gene expression analysis revealed that CIB1 is significantly overexpressed in CRC leading to liver metastases compared to M0 and PER. Thus, the present results suggest that CIB1 may play a crucial role for hematogenous spread to the liver but not for peritoneal carcinomatosis.