Nov 21, 2022 · Also has diffuse CAIX but is positive for CD10 and negative or focal for CK7; Loss of chromosome 3p commonly seen Papillary renal cell carcinoma: Clear glycogenated cytoplasm is rare Foamy macrophages and psammoma bodies are common Also usually positive for CK7 but negative or only focal CAIX and often has apical CD10 expression

Epithelial markers: low molecular weight keratin (CAM 5.2), AE1-AE3 cytokeratin cocktail, CK7, CK20, CEA and EMA Alternative epithelial markers on sarcomatoid carcinoma include p63, MOC-31 and TTF1 (Mod Pathol 2005;18:1471) Melanocytic markers: S100 (also a mesenchymal marker), HMB45, MelanA / Mart1

Sep 20, 2022 · D. INSM1+, chromogranin+, CK7- punctate, p40-, Ki67 high. The tumor shown is small cell carcinoma of the lung. Of the choices listed, INSM1+, chromogranin+, CK7- punctate, p40-, Ki67 high (answer D) is the most likely immunoprofile. …

Bladder: CK7 CK20 GATA3 p40 p63 PDL1 22C3 uroplakin II Kidney: AMACR CAIX CD10 CK7 c-kit / CD117 fumarate hydratase INI1 / SMARCB1 MelanA PAX8 RCC SDHB SMA TFE3 vimentin WT1 Penis: CK5/6 and CK5 HPV p40 p63 Prostate: AMACR androgen receptor (AR) CK5/6 and CK5 ERG NKX3.1 p63 prostein (P501S) PSA PSAP PSMA Testis: AFP CD30 CK7 c …

Jun 1, 2014 · CK7. CK5 / 6. Calretinin. Positive stains. Cytokeratin AE1 / AE3, cytokeratin 7 (CK7) Calretinin (nuclear ...

May 13, 2021 · Simultaneous expression of biliary antigens (CK7, CK19, OV6) and hepatocyte antigens (HepPar1, albumin, alpha-1 antitrypsin, biliary glycoprotein 1 detected by canalicular staining with polyclonal anti-CEA and occasionally alpha …

Oct 23, 2020 · CK7, CK20: Negative in low grade prostatic carcinoma Negative or focally positive in high grade prostatic carcinoma CDX2 can be positive Negative staining: PAX8, PAX2, TTF1, GATA3, 34 beta E12, p63, p40

Pancytokeratins and CK7 should not be used in this differential diagnosis, as both metastatic carcinoma and mesothelioma can express them (Arch Pathol Lab Med 2013;137:647, Mod Pathol 2000;13:962) Metastatic carcinoma

Oct 21, 2020 · Can be reliably distinguished from clear cell RCC by CK7, CKIT (CD117), CAIX and vimentin Classic autosomal dominant genetic correlation is Birt-Hogg-Dubé syndrome, which is associated with a mutation of the HOGG gene on chromosome 3p Fuhrman / WHO grading is useful prognostic indicator Sarcomatoid dedifferentiation is very common

CK7 positive (however, sometimes patchy in eosinophilic chromophobe) S100A1 usually negative Hybrid oncocytic / chromophobe tumors (HOCT) (Mod Pathol 2019;32:1698): Term usually applied in syndromic settings as the Birt-Hogg-Dubé associated tumors but occasionally sporadic cases can present as such