2023年10月9日 · The CKM staging model emphasizes the progressive pathophysiology of CKM syndrome, underscores the importance of early detection of CKM-related changes to support prevention efforts, and highlights the stepwise increase in absolute CVD risk associated with later stages, when intensified therapies for patients with CKM syndrome will have the ...

For each participant, we determined the CKM syndrome stage: 1 stage 0 (no CKM risk factors, such as hypertension), 1 (excess or dysfunctional adiposity), 2 (additional metabolic risk factors or moderate- or high-risk chronic kidney disease), 3 (very high-risk chronic kidney disease or high predicted 10-year CVD risk), 4 or 4 (established CVD ...

CKM syndrome stages. The CKM syndrome stages are: Stage 0: You have no risk factors. Stage 1: You have extra body fat, especially in your belly. Stage 2: You have Type 2 diabetes, high triglycerides, high blood pressure or kidney disease. Stage 3: You have early cardiovascular disease (but no symptoms) or a high risk of it.

Stage 1 CKM includes individuals with excess adipose tissue, dysfunctional adipose tissue, or both. Excess adiposity is identified by either weight or abdominal obesity, and dysfunctional adipose tissue is reflected by impaired glucose tolerance and hyperglycemia.

2024年8月8日 · CKM综合征的早期发现和干预往往与更大的临床获益相关，为了促进全生命周期心血管-肾脏-代谢健康，本文提出了CKM综合征分期的新模型（图1）： 0期：无CKM危险因素。 体重指数（BMI）和腰围正常，血糖、血压、血脂正常，无CKD或亚临床/临床CVD证据； 1期：存在过度或已引起功能异常的肥胖。 个体存在超重/肥胖、腹型肥胖或功能异常的脂肪组织，但未合并其他代谢危险因素或CKD。 BMI≥25kg/m2（亚洲人群≥23kg/m2）。

2024年11月1日 · There are five stages of CKM syndrome: Stage 0 (absence of CKM risk factors); Stage 1 (early signs of risk factors); Stage 2 (visible cardiometabolic risk factors and CKD); Stage 3 (subclinical CVD in CKM, reno-metabolic risk factors); Stage 4 (clinical CVD in CKM, with or without CKD). 4 The cluster of risk factors varies between modifiable ...

5 天之前 · CKM syndrome is measured in five stages. If you have any risk factors for CKM syndrome, it’s important to undergo regular screenings. Uncontrolled CKM syndrome can lead to serious health problems like kidney failure, heart attack, stroke, and heart failure.. Your health care team can help you identify which stage you are …

2024年11月4日 · Exposures: The exposures included 5 CKM stages (ie, stages 0-4) reflecting progressive pathophysiology, with advanced (stages 3 or 4) and nonadvanced (stages 0, 1, or 2) disease. CKM stages were defined based on risk factors for metabolic syndrome, cardiovascular disease, and chronic kidney disease.

For each participant, we determined the CKM syndrome stage: 1 stage 0 (no CKM risk factors, such as hypertension), 1 (excess or dysfunctional adiposity), 2 (additional metabolic risk factors or moderate- or high-risk chronic kidney disease), 3 (very high-risk chronic kidney disease or high predicted 10-year CVD risk), 4 or 4 (established CVD ...

2023年10月9日 · Progression along CKM stages is associated with increased relative and absolute risk for CVD, kidney failure, and mortality. Altering the trajectory of CKM syndrome requires a deeper understanding of metabolic-inflammatory interplay accompanied by an integration of bio-socio-ecological pathways.