2023年3月8日 · Charcot-Marie-Tooth disease is also called hereditary motor and sensory neuropathy. Charcot-Marie-Tooth disease results in smaller, weaker muscles. You may also experience loss of sensation and muscle contractions, and difficulty walking. Foot deformities such as hammertoes and high arches also are common.

2018年9月26日 · Charcot-Marie Tooth (CMT) disease is a condition that commonly produces a high arched foot (Figure 1). It was described independently by Jean-Martin Charcot, Pierre Marie, and Howard Henry Tooth in 1886. It is also known as Hereditary Sensorimotor Neuropathy (HSMN), or Peroneal Muscular Atrophy.

2022年11月29日 · Charcot-Marie-Tooth disease (CMT) is the name for a group of conditions that all affect how your peripheral nerves (the nerves outside of your brain and spinal cord) work. This condition usually affects muscle control and how you feel your feet and hands.

Charcot-Marie-Tooth (CMT) disease is an inherited nerve problem. It causes abnormalities in the nerves that supply your feet, legs, hands, and arms. It affects both your motor and sensory nerves.

2014年8月29日 · Those affected by Charcot-Marie-Tooth disease often display distinct physical symptoms that manifest in their feet. A basic overview of CMT foot symptoms that can be found below. High Arches and Clawfoot: The classic, very high arch is formed because the peroneal group no longer properly opposes the tibial muscles. Muscles need to be balanced.

2023年1月3日 · Charcot-Marie-Tooth Disease, also known as peroneal muscular atrophy, is a common autosomal dominant hereditary motor sensory neuropathy, caused by abnormal peripheral myelin protein, that presents with muscles weakness and sensory changes which can lead to cavovarus feet, scoliosis, and claw foot deformities.

Foot contractures resulting in high-arched feet often occur in CMT. The most common initial presentation of CMT is distal weakness and atrophy, which manifest with foot drop and pes cavus (high arched feet). Many patients with CMT eventually develop contractures (stiffened joints) that result in deformities of the feet and hands.

Your doctor may be able to help, although many are not familiar with CMT. The most common deformity in about 80 percent of patients with CMT is a cavovarus foot. The arch is high (cavus), the heel is turned inward (varus), and the toes are contracted (clawed). This abnormal foot shape results from years of imbalanced muscle-pull.

2025年2月17日 · Charcot-Marie-Tooth disease type 2 affects another part of the nerves called the axon. This can cause muscle weakness, numbness, and issues with speech or breathing. Charcot-Marie-Tooth disease type 4 is a rare, but severe form of CMT nerve disease. The symptoms often develop early on, with most people losing the ability to walk in their teen ...

Appropriate footwear is important for people with Charcot-Marie-Tooth disease (CMT), or hereditary peripheral neuropathy, but many patients struggle to find well-fitting shoes because of their high-arched feet and hammered toes.