2023年3月8日 · Charcot-Marie-Tooth disease is an inherited, genetic condition. It occurs when there are mutations in the genes that affect the nerves in your feet, legs, hands and arms.

Charcot–Marie–Tooth disease (CMT) is a hereditary motor and sensory neuropathy of the peripheral nervous system characterized by progressive loss of muscle tissue and touch …

1998年9月28日 · Charcot-Marie-Tooth (CMT) hereditary neuropathy refers to a group of disorders characterized by a chronic motor and sensory polyneuropathy, also known as hereditary motor …

There are three distinct inheritance patterns that encompass all the many variations of CMT. The most common forms of CMT are inherited in an autosomal dominant pattern. Autosomal …

This guide provides a complete accounting of CMT subtypes and identified CMT-associated genes for everyday CMTers and practicing clinicians to reference.

2025年1月6日 · Charcot-Marie-Tooth disease (CMT) is a group of genetic conditions that affect the nerves connecting the brain and spinal cord to the rest of the body. CMT is the most …

Type X Charcot-Marie-Tooth disease (CMTX) is caused by mutations in genes on the X chromosome, one of the two sex chromosomes. Within the various types of Charcot-Marie …

2024年6月22日 · Charcot-Marie-Tooth (CMT) disease is the most common inherited neuromuscular disorder, characterized by progressive weakness of the extremities due to …

Mutations in more than 30 genes affecting glial and/or neuronal functions have been associated with different forms of CMT leading to a substantial improvement in diagnostics of the disease …

CMT is a genetically heterogeneous disorder in which mutations in different genes can produce the same clinical symptoms. In CMT there are not only different genes but different patterns of …

Inherited neuropathies known as Charcot-Marie-Tooth (CMT) disease are genetically heterogeneous disorders affecting the peripheral nerves, causing significant and slowly …

2020年6月16日 · CMT is a genetic disorder, meaning it’s caused by a change, or mutation, in your genes. If you have CMT, you might be wondering how you got it. It’s likely that other people in …

2022年3月18日 · Recent research in the field of inherited peripheral neuropathies (IPNs) such as Charcot–Marie–Tooth (CMT) disease has helped identify the causative genes provided better...

Charcot-Marie-Tooth neuropathies (CMT) constitute a group of common but highly heterogeneous, non-syndromic genetic disorders affecting predominantly the peripheral …

2024年12月24日 · Charcot-Marie-Tooth Disease (CMT) is synonymous with the term hereditary motor sensory neuropathy (HMSN). CMT encompasses a range of disorders resulting from …

More than 30 genes have been implicated in CMT. In different types of CMT, peripheral nerve damage can be caused by defects in genes coding for proteins affecting axons, or by defects …

2024年12月17日 · Charcot-Marie-Tooth disease (CMT), also known as hereditary motor and sensory neuropathy, is the most common hereditary neuropathy. It is slightly more common in …

2013年12月27日 · CMT is an inherited neurological disease characterized by a slowly progressive degeneration of the muscles in the foot, lower leg, hand, and forearm, and a mild loss of …

2025年2月17日 · Charcot-Marie-Tooth disease (CMT disease) is an umbrella term for a group of genetic conditions that affect the nerves. These conditions are due to inherited genetic …

Charcot-Marie-Tooth disease (CMT) is caused by mutations (faults) in genes that cause the peripheral nerves to become damaged. The peripheral nerves are a network of nerves that run …