The enzyme-linked immunosorbent assay (ELISA) is the most common serologic test for measuring antibody to CMV. Tests for congenital CMV in newborns. Polymerase chain reaction (PCR) on saliva is the standard laboratory test for diagnosing congenital CMV infection. Urine is usually collected and tested for confirmation.

What are cytomegalovirus (CMV) tests? Cytomegalovirus (CMV) tests check for signs of CMV in your blood, sputum, or other body fluids. CMV is a virus in the herpes family. Other types of herpes viruses include the viruses that cause chickenpox and mononucleosis (mono). CMV is a common virus that infects people of all ages.

Ensure multisite accurate performance to reliably monitor transplant patients’ viral load trends over time and across geographies with the Aptima CMV Quant assay. Uses the same panel of samples to evaluate across multiple operators, instruments and locations to deliver consistent results across all variables.

Quantitative CMV PCR can be used for early detection of reactivation, primary infection and monitoring response to treatment. Dual gene targets and multiple probes increases the assay’s ability to pick up polymorphisms, therefore reducing the chance for false negatives and detecting other strains that could otherwise be missed.

1. SUMMARY OF TEST PRINCIPLE AND CLINICAL RELEVANCE The VIDAS is an automated instrument that performs an enzyme-linked fluorescent immunoassay (ELFA). The instrument controls all assay steps and assay temperature. Each CMV assay kit contains controls, standards, reagent strips, and SPR (Solid Phase Receptacle).

The cobas® CMV test reliably monitors CMV infection and is proven to provide comparable and reproducible viral load results across different institutions to reliably spot CMV and help transplant patients thrive. You can realise the following benefits for your laboratory and clinicians.

The Abbott RealTime CMV assay uses PCR technology combined with homogeneous real time fluorescent detection for the quantitation of CMV DNA. The selection of two conserved regions of CMV genome provides for the robust and accurate detection of CMV.

2025年2月1日 · Our data suggested that Alinity m CMV assay (Plasma) is suitable to detect and quantify CMV DNA in plasma but also in non-plasma samples including amniotic fluid, BAL, CSF, saliva and urine. The assay was linear and efficient in the tested range (from 1.51 Log 10 to 5.51 Log 10 IU/mL) with r > 0.98 and PCR efficiency > 90 %.

The Alinity m CMV assay is an in vitro polymerase chain reaction (PCR) assay for use with the automated Alinity m System to detect and quantitate cytomegalovirus (CMV) DNA in human plasma. The Alinity m CMV assay is intended for use as an aid in the diagnosis and management of CMV in transplant patients and other immunocompromised patients.

2020年5月15日 · Several testing methodologies are available in today’s clinical laboratories to evaluate a patient’s CMV status: viral culture, serology, histopathology, pp65 antigenemia, and quantitative PCR. In this post, we will review the advantages and limitations of these tests.