Corticotropin-releasing hormone (CRH) is a 41-amino acid peptide derived from a 196-amino acid preprohormone. CRH is secreted by the paraventricular nucleus (PVN) of the hypothalamus in …

The characterization of CRH receptors, the availability of CRH agonists and antagonists, and advanced immunocytochemical staining techniques have provided evidence that CRH plays a …

corticotropin-releasing hormone (CRH), a peptide hormone that stimulates both the synthesis and the secretion of adrenocorticotropic hormone (ACTH) in the corticotropin-producing cells …

2001年5月1日 · Dysfunctioning of corticotropin-releasing hormone (CRH) and its receptors (CRH 1 and CRH 2) has been linked to the development of stress-related disorders, such as mood …

Corticotropin releasing hormone (CRH) is essential for stress adaptation by mediating hypothalamic-pituitary adrenal (HPA) axis, behavioral and autonomic responses to stress. …

2023年1月1日 · We review and describe cellular components and molecular mechanisms involved in CRH system signaling through G protein-coupled receptors (GPCRs) CRHR1 and …

2012年1月1日 · Corticotropin releasing hormone (CRH) is essential for stress adaptation by mediating hypothalamic–pituitary–adrenal (HPA) axis, behavioral and autonomic responses to …

Corticotropin-releasing hormone (CRH) is a key player of basal and stress-activated responses in the hypothalamic–pituitary–adrenal axis (HPA) and in extrahypothalamic circuits, where it …

Corticotropin releasing hormone (CRH) is essential for stress adaptation by mediating hypothalamic-pituitary-adrenal (HPA) axis, behavioral and autonomic responses to stress. …

4 小时之前 · The elevation of glucocorticoids is a hallmark of stress, arising from the integration of rapid neuronal signals into sustained hormonal outputs. A key interface for this …