
Dissection of the PVN CRH to DMV ChAT pathway. (A) Schematic …
To confirm the PVN CRH → DMV projection, we applied a cell typespecific anterograde tracking system and injected the anterograde rAAV-DIO-ChR2-EYFP virus into the PVN of the CRH …
Nat Neurosci:中科大张智团队报道疼痛调控免疫的新神经环路机 …
2024年2月5日 · 最近很多研究旨在了解大脑与外周免疫细胞沟通的机制,有研究发现下丘脑室旁核(pvn)的促肾上腺皮质激素释放激素(crh)神经元与脾神经之间存在联系,这种联系介导与 …
A neural circuit for gastric motility disorders driven by gastric ...
2023年2月22日 · The neural pathway associated with gastric motility disorders was investigated by behavioral tests, electrophysiology, neural circuit tracing, and optogenetics and …
A neural circuit for gastric motility disorders driven by gastric ...
2023年2月21日 · We used viral tracking nuclear electrophysiology to identify an inhibitory neural circuit of the PVN CRH → DMV ChAT pathway. Following this, the activity of this circuit was …
Dissection of the PVNCRH to DMVChAT pathway. (A
Postoperative delayed gastric emptying is a prevalent complication following surgical procedures, imposing heavy physical and financial burdens on patients. However, current treatment options...
中国科学技术大学刘际团队揭示下丘脑-交感神经-肝轴调控应激性 …
2024年10月7日 · 进一步电生理实验发现crh通过减少gabaa受体转运到突触后膜进而抑制vmh-sf-1神经元的抑制性突触后电流。大多数gabaa受体由2α, 2β 和 1γ亚基组成,其中 ...
An integrated single‐cell RNA‐seq atlas of the mouse …
We identify Avp - Tac1, Avp - Th, Oxt - Foxp1, Crh - Nr3c1, and Trh - Nfib as the most important neuroendocrine subtypes based on markers described in literature. To characterize the …
顶刊综述 | Science(IF: 63.7): 通过肠-脑轴传递的炎症信号机制
2022年10月2日 · 先天性和适应性免疫系统通过协同工作来应对肠道的应激反应,先天性免疫细胞包括树突状细胞(DCs)、M细胞、巨噬细胞、肥大细胞、自然杀伤细胞,以及1型、2型和3 …
刘际团队揭示下丘脑-交感神经-肝轴调控应激性即时高血糖反应机 …
2024年10月10日 · 进一步电生理实验发现crh通过减少gabaa受体转运到突触后膜进而抑制vmh-sf-1神经元的抑制性突触后电流。大多数gabaa受体由2α, 2β 和 1γ亚基组成,其中crh仅降 …
Optogenetic modulation of the PVN CRH → DMV ChAT
We injected the cre-dependent inhibitory optogenetic virus rAAV-DIO-eNpHR3-EYFP into the bilateral PVN and buried optical fibers in the bilateral DMV (Figures 5A, B). The optical …