The NCI Common Terminology Criteria for Adverse Events is a descriptive terminology which can be utilized for Adverse Event (AE) reporting. A grading (severity) scale is provided for each AE …

Drug-induced ototoxicity should be distinguished from age-related threshold decrements or unrelated cochlear insult. When considering whether an adverse event has occurred, it is first …

In a comparison between outcomes of four ototoxicity scales in 319 adult patients treated with chemo-radiation or radiation therapy alone for head and neck cancer, the prevalence of …

2010年3月1日 · Clinical trials report ototoxicity as an adverse event based on a numeric grading system, the National Cancer Institute Common Terminology Criteria for Adverse Events …

2011年12月1日 · Pure-tone audiograms were evaluated using the newly proposed grading criteria, Brock criteria, and Common Terminology Criteria for Adverse Events (CTCAE). The …

According to the most recent version of the NCI CTCAE (version 5.0), hearing loss is graded differently for children versus adults, on a scale of Grade 1 to Grade 4. There is no Grade 5 …

2010年4月1日 · This grading system provides robust and clinically useful criteria to represent clinical hearing loss induced by ototoxicity with regard to the impact on speech and language …

Pure-tone audiograms were evaluated using the newly proposed grading criteria, Brock criteria, and Common Terminology Criteria for Adverse Events (CTCAE). The resulting grades were …

Although widely used, the CTCAE criteria do not include HFA, which, as previously discussed, can be very useful in the early detection of ototoxicity. Additionally, the CTCAE criteria include …

2011年11月22日 · Pure-tone audiograms were evaluated using the newly proposed grading criteria, Brock criteria, and Common Terminology Criteria for Adverse Events (CTCAE). The …